Clinically-significant Gram-negative species remain mostly Enterobacteriaceae,
Pseudomonas aeruginosa and Acinetobacter baumannii. Carbapenem molecules are often …

Carbapenem resistance is a major and an on-going public health problem globally. It occurs
mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas …

Singapore is an international travel and medical hub and faces a genuine threat for import
and dissemination of bacteria with broad-spectrum resistance. In this review, we described …

Carbapenem resistance, mainly among Gram-negative pathogens, is an ongoing public-
health problem of global dimensions. This type of antimicrobial resistance, especially when …

Acquired resistance to carbapenems is uncommon in Enterobacteriaceae [1, 2], although
extendedspectrum b-lactamase-mediated resistance in these organisms is well established …

Acquired resistance in carbapenem-resistant Enterobacteriaceae (CRE) conferred by
carbapenemases is a major concern worldwide. Consecutive, non-duplicate isolates of …

The emergence and spread of carbapenem-resistant gram-negative bacteria poses a
serious threat to human health worldwide. Currently, little is known about the molecular …

Infections with carbapenemase-producing Gram-negative bacteria are related to increased
morbidity and mortality, yet little is known regarding infections caused by non-beta …

The first reports of carbapenem resistance in Enterobacteriaceae isolates occurred in the
early 1990s. Researchers published the first report of an isolate that produced Klebsiella …

Pseudomonas aeruginosa and some of the species of Enterobacteriaceae are Gram-
negative hospital-acquired pathogens that are mostly difficult to treat. Carbapenem drugs …