The fusion of fluorine in drug molecules through different fluorinating reagents remains a
cornerstone in pharmaceutical chemistry. Progress in the field of deoxyfluorination through …

Fluoroacetate dehalogenase catalyzes the hydrolytic defluorination of fluoroacetate to
produce glycolate. The enzyme is unique in that it catalyzes the cleavage of the highly stable …

Fluorine and Health presents a critical multidisciplinary overview on the contribution of
fluorinated compounds to resolve the important global issue of medicinal monitoring and …

Fluorine is the thirteenth most abundant element in the earth's crust, but fluoride
concentrations in surface water are low and fluorinated metabolites are extremely rare,. The …

Organofluorine compounds are widely prepared throughout the chemicals industry, but their
prepararion generally requires harsh fluorinating reagents and non-aqueous solvents. On …

Transition metal catalyzed transformations using fluorinating reagents have been developed
extensively for the preparation of synthetically valuable fluorinated targets. This is a topic of …

Fluorine‐containing molecules have attracted much attention in medicinal, agrochemical,
and materials sciences because they offer unique physical and biological properties …

Investigations on diverse aspects of fluoro-organic compounds have rapidly increased
during the past decades. Because natural sources of fluoro-organic compounds are …

Numerous procedures focus on inserting the fluorine atom into the carbon frameworks of
synthetically useful target molecules using various nucleophilic fluorinating reagents …

In the synthesis of bio-active compounds, fluorinated compounds play a prominent role.
However, the site-selective fluorination of organic molecules is often challenging, because …