Fluorinated amino acids serve as an entry point for establishing new-to-Nature chemistries
in biological systems, and novel methods are needed for the selective synthesis of these …

Fluoro-organic biochemistry Page 1 Timothy B. Patrick Southern Illinois University
Edwardsville, 62026 Fluoro-Organic Biochemistry Fluoro-organic chemistry has made a …

Organofluorine compounds often possess unique chemical, physical and biological
properties and therefore, they play important roles in pharmaceuticals, agrochemicals, and …

Optimisation and real time reaction monitoring of the synthesis of 2-fluoromalonate esters by
direct fluorination using fluorine gas is reported. An assessment of green metrics including …

Aryl and heteroaryl fluorides are growing to be dominant motifs in pharmaceuticals and
agrochemicals, yet they are rare in both nature and commodity chemicals. As a …

Incorporation of fluorine into organic molecules is a well-established strategy in the design
of advanced materials, agrochemicals, and pharmaceuticals. Among numerous modern …

Fluorinated organic molecules are increasingly being prepared for a variety of applications,
including pharmaceutical products. However, the supply chain to access the necessary raw …

Organofluorine compounds have found widespread applications in the pharmaceutical and
agrochemical industries. Efficient construction of organofluorine molecules is highly …

Despite the abundance of fluorine in the Earth's crust naturally occurring organofluorine
compounds are comparatively rare in nature with those isolated to date totalling no more …

Fluorine is a critical element for the design of bioactive compounds, driving advances in
selective and sustainable fluorination. However, stereogenic tertiary fluorides pose a …