Streptomyces cattleya is unusual in that it elaborates organofluorine metabolites and in
particular secretes fluoroacetate and 4-fluorothreonine as secondary metabolites when …

The use of inner triple bonds produced mainly the perfluoroalkanoic acids directly from
perfluoroalkyl iodides in water at room temperature. When lipoxygenase was used in a 2 …

Trifluoromethylated alkenes and alkynes are versatile building blocks for organofluorine
synthesis. In addition,(trifluoromethyl) alkene motifs are found in biofunctional molecules …

The unique and desirable properties of fluorinated compounds in pharmaceutical,
agrochemical, and materials sciences have driven the development of remote fluorination …

A concise and efficient hydrodefluorination process was developed for the synthesis of gem-
difluoroalkenes. This reaction employs rongalite as a masked proton source and does not …

Efficient fluoroalkylations have been proven to be a highly useful strategy for the synthesis of
bioactive fluorine-containing compounds and other materials. The design and use of a …

Fluorinated compounds can exhibit interesting biological properties. The importance of
these species has made that the chemistry of fluorine has experienced a great development …

Abstract gem-Difluoromethylene substituted molecules constitute a distinct class of
fluorinated compounds. In this study, special chemistry has been developed for their …

Fluoroaromatics are widely and—in recent years—increasingly used as agrochemicals,
starting materials for chemical syntheses and especially pharmaceuticals. This originates …

Introducing fluorine or fluorine‐containing groups into organic compounds or biologically
active compounds to improve their physical and chemical properties such as membrane …