Insertions, substitutions, and the origin of microsatellites

Y Zhu, JE Strassmann, DC Queller - Genetics Research, 2000 - cambridge.org
This paper uses data from the Human Gene Mutation Database to contrast two hypotheses
for the origin of short DNA repeats: substitutions and insertions that duplicate adjacent …

Microsatellites: evolution and mutational processes

NB Freimer, M Slatkin - … 197‐Variation in the Human Genome …, 2007 - Wiley Online Library
Microsatellites (simple sequence repeats) are ubiquitous in eukaryotic genomes, and they
are highly polymorphic. They are currently the primary tools for most genetic mapping and …

The mutational spectrum of human autosomal tetranucleotide microsatellites

AM Leopoldino, SDJ Pena - Human Mutation, 2003 - Wiley Online Library
We studied by multiplex amplification and single‐run electrophoretic analysis 10
microsatellite loci, composed of nine tetranucleotide‐repeats (D1S1612, D3S2387 …

Mutation rate in human microsatellites: influence of the structure and length of the tandem repeat

B Brinkmann, M Klintschar, F Neuhuber… - The American Journal of …, 1998 - cell.com
Summary In 10,844 parent/child allelic transfers at nine short-tandem-repeat (STR) loci, 23
isolated STR mismatches were observed. The parenthood in each of these cases was highly …

Microsatellite evolution: a battle between replication slippage and point mutation

H Ellegren - TRENDS in Genetics, 2002 - cell.com
Pick a eukaryotic genome and initiate shot-gun sequencing–you will not have to sequence
too many clones until you start seeing simple tandem repeat sequences, such as …

The exact numbers of possible microsatellite motifs.

L Jin, Y Zhong, R Chakraborty - American journal of human …, 1994 - ncbi.nlm.nih.gov
Several efforts have been made to study the distributions and frequencies of microsatellites
in the genomes of various organisms by searching the existing GenBank sequences (Weber …

Microsatellites and other simple sequences: genomic context and mutational mechanisms

JM Hancock - Microsatellites: Evolution and applications, 1999 - cir.nii.ac.jp
抄録< jats: title> Abstract</jats: title>< jats: p>'Microsatellite'is now the commonest term used
to describe tandem repeats of short sequence motifs (no more than six bases long) …

Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineages

DC Rubinsztein, B Amos… - … Transactions of the …, 1999 - royalsocietypublishing.org
Microsatellites are stretches of repetitive DNA, where individual repeat units comprise one to
six bases. These sequences are often highly polymorphic with respect to repeat number and …

Mutation rate in human microsatellites.

J Henke, L Henke - American journal of human genetics, 1999 - ncbi.nlm.nih.gov
It is common knowledge that mutation rates of DNA (minisatellite and microsatellite) loci can
differ by orders of magnitude. Obviously, the mutation rate is closely related to the degree of …

Survey of human and rat microsatellites

JS Beckmann, JL Weber - Genomics, 1992 - Elsevier
Length variations in simple sequence tandem repeats (microsatellite DNA polymorphisms)
are finding increasing usage in mammalian genetics. Although every variety of short tandem …