PH20 is a member of the human hyaluronidase family that degrades hyaluronan in the
extracellular matrix and controls tumor progression. Inhibition of DNA methyltransferases …

TUDOR domain–containing proteins (TDRDs) are chiefly responsible for recognizing methyl-
lysine/arginine residue. However, how TDRD dysregulation contributes to breast …

Background Mounting evidence supports that long noncoding RNAs (lncRNAs) have critical
roles during cancer initiation and progression. In this study, we report that the plasmacytoma …

Histone demethylase PHF8 is upregulated and plays oncogenic roles in various cancers;
however, the mechanisms underlying its dysregulation and functions in carcinogenesis …

PR domain zinc finger protein 14 (PRDM14) maintains stemness in embryonic stem cells via
epigenetic mechanisms. Although PRDM14 is elevated in several cancers, it is unclear if …

Alterations in the ubiquitin-proteasome system (UPS) and UPS-associated proteins have
been implicated in the development of many human malignancies. In this study, we …

Triple-negative breast cancer (TNBC) is one of the most common malignant tumor types in
females and its drug resistance is a major clinical issue. An increasing number of long non …

Accumulating evidence indicates that long non-coding RNAs (lncRNAs) play a key role in
the development of many human cancers. MT1JP is a lncRNA that is reportedly involved in …

Breast cancer has become a leading cause of cancer-related deaths in women worldwide.
DNA methylation has been revealed to play an enormously important role in the …

Background NUDT21, an RNA binding protein, has been reported to play an important role
in the regulation of multiple biological responses. Detection of NUDT21 expression may …