Liposomes as carriers of hydrophilic small molecule drugs: strategies to enhance encapsulation and delivery
JO Eloy, MC de Souza, R Petrilli, JPA Barcellos… - Colloids and surfaces B …, 2014 - Elsevier
Although hydrophilic small molecule drugs are widely used in the clinic, their rapid
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …
clearance, suboptimal biodistribution, low intracellular absorption and toxicity can limit their …
Trends and developments in liposome drug delivery systems
T Lian, RJY Ho - Journal of pharmaceutical sciences, 2001 - Elsevier
Since the discovery of liposomes or lipid vesicles derived from self‐forming enclosed lipid
bilayers upon hydration, liposome drug delivery systems have played a significant role in …
bilayers upon hydration, liposome drug delivery systems have played a significant role in …
Stimulus-responsive liposomes for biomedical applications
AI Antoniou, S Giofrè, P Seneci, D Passarella… - Drug discovery today, 2021 - Elsevier
Liposomes are amphipathic lipidic supramolecular aggregates that are able to encapsulate
and carry molecules of both hydrophilic and hydrophobic nature. They have been widely …
and carry molecules of both hydrophilic and hydrophobic nature. They have been widely …
[PDF][PDF] Liposomal drug delivery: a versatile platform for challenging clinical applications
Liposomes are lipid based vesicular systems that offer novel platform for versatile drug
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …
delivery to target cell. Liposomes were first reported by Bangham and his co-workers in …
Design of liposomal formulations for cell targeting
E Nogueira, AC Gomes, A Preto… - Colloids and surfaces B …, 2015 - Elsevier
Liposomes have gained extensive attention as carriers for a wide range of drugs due to
being both nontoxic and biodegradable as they are composed of substances naturally …
being both nontoxic and biodegradable as they are composed of substances naturally …
[HTML][HTML] Stimulus-responsive liposomes as smart nanoplatforms for drug delivery applications
Liposomes are known to be promising nanoparticles (NPs) for drug delivery applications.
Among the different types of self-assembled NPs, liposomes stand out for their non-toxic …
Among the different types of self-assembled NPs, liposomes stand out for their non-toxic …
Small molecule therapeutic-loaded liposomes as therapeutic carriers: from development to clinical applications
While small hydrophilic therapeutic molecules have proved to be exceptionally effective in
curing diseases, their in vivo efficacy remains low. Small molecule therapeutics infused in …
curing diseases, their in vivo efficacy remains low. Small molecule therapeutics infused in …
Ligand-targeted liposomes
E Forssen, M Willis - Advanced drug delivery reviews, 1998 - Elsevier
Liposomes have gained increased attention as systemic drug delivery vehicles following
recent regulatory approvals of several vesicle-formulated drugs. These products have …
recent regulatory approvals of several vesicle-formulated drugs. These products have …
[HTML][HTML] Advances and challenges of liposome assisted drug delivery
L Sercombe, T Veerati, F Moheimani, SY Wu… - Frontiers in …, 2015 - frontiersin.org
The application of liposomes to assist drug delivery has already had a major impact on
many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic …
many biomedical areas. They have been shown to be beneficial for stabilizing therapeutic …
Active methods of drug loading into liposomes: recent strategies for stable drug entrapment and increased in vivo activity
J Gubernator - Expert opinion on drug delivery, 2011 - Taylor & Francis
Introduction: The use of liposomes increases the therapeutic index of many drugs, and also
offers drug targeting and controlled release. The commercial impact of liposomes is …
offers drug targeting and controlled release. The commercial impact of liposomes is …