Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin …

SN Chang, M Haroon, DK Dey, SC Kang - The Journal of Nutritional …, 2022 - Elsevier
Rhabdomyolysis induced acute kidney injury (RIAKI) is a life-threatening condition
responsible for approximately 19-58% of AKI cases worldwide. We performed an …

Rhabdomyolysis induced AKI via the regulation of endoplasmic reticulum stress and oxidative stress in PTECs

Y Feng, L Ma, L Liu, HG Hong, X Zhang, F Guo… - RSC …, 2016 - pubs.rsc.org
Although rhabdomyolysis-associated acute kidney injury (AKI) is a life-threatening clinical
condition that accounts for about 10–40% of AKI cases, the mechanism underlying …

Perspective on rhabdomyolysis-induced acute kidney injury and new treatment options

S Ulusoy, G Ozkan, M Alkanat, S Mungan… - American journal of …, 2013 - karger.com
Aim: The purpose of this study was to assess the role of caspase-dependent apoptosis,
caspase 1, calpain 1, inducible nitric oxide synthase (iNOS) and endothelial nitric oxide …

[HTML][HTML] Protective effect of citronellol in rhabdomyolysis-induced acute kidney injury in mice

YS Mahmood, SH Kathem - Journal of Medicine and Life, 2023 - ncbi.nlm.nih.gov
Acute kidney injury (AKI) is a serious pathophysiological event consequent to
rhabdomyolysis. Inflammatory mechanisms play a role in the development of …

Diacerein protects against glycerol-induced acute kidney injury: modulating oxidative stress, inflammation, apoptosis and necroptosis

RN Abd-Ellatif, II Hegab, MM Atef, MT Sadek… - Chemico-biological …, 2019 - Elsevier
Necroptosis is suggested to have an important role in the pathogenesis of rhabdomyolysis
induced acute kidney injury (AKI). In this study, the renoprotective effect of diacerein on …

Agmatine attenuates rhabdomyolysis-induced acute kidney injury in rats in a dose dependent manner

MH Sharawy, RS Abdelrahman, DH El-Kashef - Life sciences, 2018 - Elsevier
Acute kidney injury (AKI) is a serious disorder that accompanies rhabdomyolysis (RM). The
underlying mechanisms as well as protective approaches need to be investigated. This …

Ramipril blunts glycerol-induced acute renal failure in rats through its antiapoptosis, anti-inflammatory, antioxidant, and renin-inhibiting properties

AA Adedapo, ER Osaretin, OO Falayi… - Journal of Basic and …, 2021 - degruyter.com
Objectives Acute kidney injury (AKI) is a malady with a sudden onset resulting in buildup of
waste matters in the body, but a specific cure hasn't been found as a lasting solution to AKI …

Oleuropein suppresses oxidative, inflammatory, and apoptotic responses following glycerol-induced acute kidney injury in rats

M Yin, N Jiang, L Guo, Z Ni, AY Al-Brakati, MS Othman… - Life sciences, 2019 - Elsevier
Aim Here, we evaluated the possible protective effects of oleuropein, the major phenolic
constituent in virgin olive oil against glycerol-induced acute kidney injury (AKI) in rats. Main …

Carnosine and crocin ameliorate oxidative stress in rats with rhabdomyolysis-induced acute kidney injury through upregulating HO-1 gene expression

NE El-Ashmawy, EG Khedr, AS Doghish, MS Elballal - Food Bioscience, 2022 - Elsevier
We aimed to investigate whether carnosine (a natural dipeptide found in humans) and
crocin (a natural product extracted from saffron and gardenia) can prevent the harmful …

Oxidative stress and inflammasome activation in human rhabdomyolysis-induced acute kidney injury

A Grivei, KTK Giuliani, X Wang, J Ungerer… - Free Radical Biology …, 2020 - Elsevier
Acute kidney injury (AKI) is a life-threatening complication of rhabdomyolysis. The
pathophysiological mechanisms of rhabdomyolysis-induced AKI (RIAKI) have been …