Dynamics of cerebral blood volume during and after middle cerebral artery occlusion in rats–Comparison between ultrafast ultrasound and dynamic susceptibility …

BAA Franx, F Lebrun, L Chin Joe Kie… - Journal of Cerebral …, 2024 - journals.sagepub.com
Tomographic perfusion imaging techniques are integral to translational stroke research
paradigms that advance our understanding of the disease. Functional ultrasound (fUS) is an …

Transcranial contrast-enhanced ultrasound in the rat brain reveals substantial hyperperfusion acutely post-stroke

D Premilovac, SJ Blackwood… - Journal of Cerebral …, 2020 - journals.sagepub.com
Direct and real-time assessment of cerebral hemodynamics is key to improving our
understanding of cerebral blood flow regulation in health and disease states such as stroke …

Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke

C Brunner, NL Denis, K Gertz, M Grillet… - Journal of Cerebral …, 2024 - journals.sagepub.com
Ischemic stroke occurs abruptly causing sudden neurologic deficits, and therefore, very little
is known about hemodynamic perturbations in the brain immediately after stroke onset …

Mapping the dynamics of brain perfusion using functional ultrasound in a rat model of transient middle cerebral artery occlusion

C Brunner, C Isabel, A Martin… - Journal of Cerebral …, 2017 - journals.sagepub.com
Following middle cerebral artery occlusion, tissue outcome ranges from normal to infarcted
depending on depth and duration of hypoperfusion as well as occurrence and efficiency of …

Ultrasound biomicroscopy in the quantification of brain perfusion parameters of a rat stroke model: Analysis of contrast agent bolus kinetic dynamics

AS da Cruz, MM Drehmer, W Baetas-da-Cruz… - Journal of Neuroscience …, 2024 - Elsevier
Background Ischemic stroke represents a significant global health concern, necessitating
thorough investigations and the utilization of stroke animal models to explore novel …

Commentary to Brain-wide continuous functional ultrasound imaging for real-time monitoring of hemodynamics during ischemic stroke

TS Nowak Jr, TD Farr - Journal of Cerebral Blood Flow & …, 2024 - journals.sagepub.com
Functional ultrasound (FUS) has emerged as a novel imaging method to reliably assess
relative cerebral blood volume (rCBV) and infer perfusion, with good spatiotemporal …

[HTML][HTML] Early Ultrafast Ultrasound Imaging of Cerebral Perfusion correlates with Ischemic Stroke outcomes and responses to treatment in Mice

V Hingot, C Brodin, F Lebrun, B Heiles, A Chagnot… - Theranostics, 2020 - ncbi.nlm.nih.gov
In the field of ischemic cerebral injury, precise characterization of neurovascular
hemodynamic is required to select candidates for reperfusion treatments. It is thus admitted …

Quantification of blood flow and volume in arterioles and venules of the rat cerebral cortex using functional micro-ultrasound

ME van Raaij, L Lindvere, A Dorr, J He, B Sahota… - Neuroimage, 2012 - Elsevier
Relative cerebral blood volume (rCBV), relative cerebral blood flow (rCBF), and blood flow
speed are key parameters that characterize cerebral hemodynamics. We used contrast …

Dynamic assessment of brain perfusion in a middle cerebral artery occlusion rat model by contrast-enhanced ultrasound imaging: a pilot study

C Zhou, X Zhu, J Li, Y Luo, Y Zhou - Acta Radiologica, 2023 - journals.sagepub.com
Background The middle cerebral artery occlusion model (MCAo) is a commonly used animal
model for cerebral ischemia studies but lacks accessible imaging techniques for the …

Combined contrast-enhanced ultrasound and rt-PA treatment is safe and improves impaired microcirculation after reperfusion of middle cerebral artery occlusion

M Nedelmann, N Ritschel, S Doenges… - Journal of Cerebral …, 2010 - journals.sagepub.com
In monitoring of recanalization and in sonothrombolysis, contrast-enhanced ultrasound
(CEUS) is applied in extended time protocols. As extended use may increase the probability …