[HTML][HTML] Genetic determinants for prediction of outcome of patients with papillary thyroid carcinoma

AA Póvoa, E Teixeira, MR Bella-Cueto, R Batista… - Cancers, 2021 - mdpi.com
Simple Summary Aggressive metastatic disease is rare in papillary thyroid carcinoma (PTC),
a neoplasia that usually carries an excellent prognosis. BRAF, RAS, and TERT promoter …

[HTML][HTML] A six-genotype genetic prognostic model for papillary thyroid cancer

X Shen, R Liu, M Xing - Endocrine-related cancer, 2017 - erc.bioscientifica.com
A unique prognostic role of the genetic duet of BRAF V600E and TERT promoter mutations
in papillary thyroid cancer (PTC) has been recently established, but the role of RAS mutation …

Prognostic implication of BRAF and TERT promoter mutation combination in papillary thyroid carcinoma—a meta‐analysis

HG Vuong, AMA Altibi, UNP Duong… - Clinical …, 2017 - Wiley Online Library
Introduction The use of molecular markers, especially BRAF and TERT promoter mutations,
for risk stratification in papillary thyroid carcinoma (PTC) is subject to continuing debate. In …

[HTML][HTML] A meta-analysis of prognostic roles of molecular markers in papillary thyroid carcinoma

HG Vuong, UNP Duong, AMA Altibi… - Endocrine …, 2017 - ec.bioscientifica.com
The prognostic role of molecular markers in papillary thyroid carcinoma (PTC) is a matter of
ongoing debate. The aim of our study is to investigate the impact of RAS, BRAF, TERT …

[HTML][HTML] TERT Promoter Mutations and Their Impact on Gene Expression Profile in Papillary Thyroid Carcinoma

D Rusinek, A Pfeifer, M Cieslicka, M Kowalska… - Cancers, 2020 - mdpi.com
Background: Telomerase reverse transcriptase promoter (TERT p) mutations are related to a
worse prognosis in various malignancies, including papillary thyroid carcinoma (PTC). Since …

[HTML][HTML] Mutations of the TERT promoter are associated with aggressiveness and recurrence/distant metastasis of papillary thyroid carcinoma

R Liu, Y Li, W Chen, J Cong, Z Zhang… - Oncology …, 2020 - spandidos-publications.com
Several previous studies have shown that mutations in B‑Raf proto‑oncogene (BRAF) and
telomerase reverse transcriptase (TERT) can be used for the diagnosis and prognosis of …

[HTML][HTML] BRAF and TERT promoter mutations in the aggressiveness of papillary thyroid carcinoma: a study of 653 patients

L Jin, E Chen, S Dong, Y Cai, X Zhang, Y Zhou… - Oncotarget, 2016 - ncbi.nlm.nih.gov
The role of telomerase reverse transcriptase (TERT) gene promoter mutations in the
aggressiveness of papillary thyroid cancer (PTC) remains to be further investigated. Here we …

Mortality risk stratification by combining BRAF V600E and TERT promoter mutations in papillary thyroid cancer: genetic duet of BRAF and TERT promoter mutations in …

R Liu, J Bishop, G Zhu, T Zhang, PW Ladenson… - JAMA …, 2017 - jamanetwork.com
Importance BRAF V600E andTERTpromoter mutations can coexist in papillary thyroid
cancer (PTC). This genetic duet was indicated to be involved in the aggressiveness of PTC …

Association of TERT promoter mutation, but not BRAF mutation, with increased mortality in PTC

JR George, YC Henderson, MD Williams… - The Journal of …, 2015 - academic.oup.com
Context: Papillary thyroid carcinoma (PTC) carrying the BRAF mutation has been reported to
be associated with high recurrence and potentially increased mortality. PTC carrying the …

The predictive value of coexisting BRAFV600E and TERT promoter mutations on poor outcomes and high tumour aggressiveness in papillary thyroid carcinoma: A …

B Chen, Y Shi, Y Xu, J Zhang - Clinical endocrinology, 2021 - Wiley Online Library
BRAFV600E mutation is highly prevalent in patients with papillary thyroid carcinoma (PTC),
and TERT promoter (TERTp) mutation is strongly associated with cancer‐related mortality …