The hot water and 70% ethanol extracts of dried mad-dog skullcap (Scutellaria lateriflora)
both bound to the 5-HT7 receptor, with 87.2±6.2% and 56.7±1.3% inhibition of [3H]-LSD …

The traditional Japanese phytomedicine rikkunshito is traditionally used for the treatment of
gastrointestinal motility disorders, cachexia and nausea. These effects indicate 5-HT3 …

MATERIALS AND METHODS Plant Materials The root of C. sinica was collected at
Changnyeong-gun, Gyeongsangnam-do, Korea in July 1995 and the plant was identified by …

5-HT7 receptor antagonists generated antidepressant-like effects in animal model and the
involvement of the 5-HT7 receptor in other pathophysiological mechanisms such as …

Insomnia is the most frequently encountered sleep complaint worldwide. While many
prescription drugs are used to treat insomnia, extracts of valerian (Valeriana officinalis L …

Different extracts (ethanolic, hexane, aqueous) of ginger (rhizomes of Zingiber officinale)
and the essential oil were tested using [14 C] guanidinium influx into N1E-115 cells and the …

Twenty-four compounds of 4-methoxy-N-[3-(4-substituted phenyl-piperazine-1-yl) propyl]
benzene sulfonamides and N-[3-(4-substituted phenyl-piperazine-1-yl) propyl] naphthyl …

A G-protein-coupled receptor (5-HT2Lym) resembling members of the 5-HT2 receptor
subfamily was cloned from the mollusc Lymnaea stagnalis. Serotonin induces a …

N-Methyllaurotetanine (1) has been reported to display good affinity for the 5-HT1A receptor,
but no structure–affinity studies have been performed to date. The commercially available …

Abstract Serotonin receptor type 3 (5-HT 3 receptor) is a ligand-gated ion channel that is
expressed in the central nervous system (CNS) as well as in the peripheral nervous system …