Autonomic dysreflexia after spinal cord injury: central mechanisms and strategies for prevention

LC Weaver, DR Marsh, D Gris, A Brown… - Progress in brain …, 2006 - Elsevier
Spinal reflexes dominate cardiovascular control after spinal cord injury (SCI). These reflexes
are no longer restrained by descending control and they can be impacted by degenerative …

Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex

H Prüss, A Tedeschi, A Thiriot, L Lynch… - Nature …, 2017 - nature.com
Acute spinal cord injury (SCI) causes systemic immunosuppression and life-threatening
infections, thought to result from noradrenergic overactivation and excess glucocorticoid …

Emerging targets for reprograming the immune response to promote repair and recovery of function after spinal cord injury

FH Brennan, PG Popovich - Current opinion in neurology, 2018 - journals.lww.com
Emerging targets for reprograming the immune response to pro... : Current Opinion in Neurology
Emerging targets for reprograming the immune response to promote repair and recovery of …

[HTML][HTML] Consequences of spinal cord injury on the sympathetic nervous system

MJ Wulf, VJ Tom - Frontiers in cellular neuroscience, 2023 - frontiersin.org
Spinal cord injury (SCI) damages multiple structures at the lesion site, including ascending,
descending, and propriospinal axons; interrupting the conduction of information up and …

Impaired antibody synthesis after spinal cord injury is level dependent and is due to sympathetic nervous system dysregulation

KM Lucin, VM Sanders, TB Jones, WB Malarkey… - Experimental …, 2007 - Elsevier
Individuals with spinal cord injury (SCI) are highly susceptible to infection. This post-
traumatic immune suppression is thought to occur via alterations in sympathetic nervous …

[HTML][HTML] Splenic sympathetic signaling contributes to acute neutrophil infiltration of the injured spinal cord

S Monteiro, AG Pinho, M Macieira… - Journal of …, 2020 - Springer
Background Alterations in the immune system are a complication of spinal cord injury (SCI)
and have been linked to an excessive sympathetic outflow to lymphoid organs. Still …

[HTML][HTML] Chronic pain after spinal cord injury: is there a role for neuron-immune dysregulation?

SS Chambel, I Tavares, CD Cruz - Frontiers in Physiology, 2020 - frontiersin.org
Spinal cord injury (SCI) is a devastating event with a tremendous impact in the life of the
affected individual and family. Traumatic injuries related to motor vehicle accidents, falls …

[HTML][HTML] Immune response following traumatic spinal cord injury: Pathophysiology and therapies

RC Sterner, RM Sterner - Frontiers in immunology, 2023 - frontiersin.org
Traumatic spinal cord injury (SCI) is a devastating condition that is often associated with
significant loss of function and/or permanent disability. The pathophysiology of SCI is …

Manipulating neuroinflammatory reactions in the injured spinal cord: back to basics

PG Popovich, TB Jones - Trends in pharmacological sciences, 2003 - cell.com
Recruitment of inflammatory leukocytes to the injured spinal cord is a physiological
response that is associated with the production of cytokines and proteinases that are …

Spinal interneurons as gatekeepers to neuroplasticity after injury or disease

LV Zholudeva, VE Abraira… - Journal of …, 2021 - Soc Neuroscience
Spinal interneurons are important facilitators and modulators of motor, sensory, and
autonomic functions in the intact CNS. This heterogeneous population of neurons is now …