Traumatic injuries of the central nervous system (CNS) affect millions of people worldwide,
and they can lead to severely damaging consequences such as permanent disability and …

Post‐traumatic immune suppression renders individuals with spinal cord injury (SCI)
susceptible to infection. Normally, proper immune function is regulated by collaboration …

Spinal serotonergic pathways provide inhibitory and excitatory modulation of sensory,
autonomic, and motor processing. After spinal cord injury (SCI), the acute inflammatory …

Denervation-induced plastic changes impair locomotor recovery after spinal cord injury
(SCI). Spinal motoneurons become hyperexcitable after SCI, but the plastic responses of …

In the injured central nervous system (CNS), reactive astrocytes form a glial scar and are
considered to be detrimental for axonal regeneration, but their function remains elusive …

In the chronic stage of spinal cord injury in humans, both innocuous and noxious somatic
and visceral stimuli can elicit severe autonomic dysreflexia characterized by potentially …

Tissues within the central nervous system (CNS) have generally been regarded as
immunologically privileged. However, in recent decades, it has been shown that immune …

Trauma to the central nervous system (CNS) triggers intraparenchymal inflammation and
activation of systemic immunity with the capacity to exacerbate neuropathology and …

Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

Traumatic spinal cord injury (SCI) causes widespread damage to neurons, glia and
endothelia located throughout the spinal parenchyma. In response to the injury, resident and …