Regulation of natural killer cell activity

SE Kirwan, DN Burshtyn - Current opinion in immunology, 2007 - Elsevier
Information regarding the role of natural killer (NK) cells in the response to viruses,
intracellular bacteria and parasites continues to emerge. NK cells can directly lyse infected …

Natural killer cells and viral infections

AR French, WM Yokoyama - Current opinion in immunology, 2003 - Elsevier
Natural killer (NK) cells play a key role in innate host defense against viruses. Significant
progress has been made in understanding the specific response of NK cells during viral …

Signal transduction during activation and inhibition of natural killer cells

C Watzl, EO Long - Current protocols in immunology, 2010 - Wiley Online Library
Natural killer (NK) cells are important for early immune responses to viral infections and
cancer. Upon activation, NK cells secrete cytokines and chemokines, and kill sensitive target …

[HTML][HTML] Natural killer cell regulation-beyond the receptors

C Watzl, D Urlaub, F Fasbender, M Claus - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Natural killer (NK) cells are lymphocytes that are important for early and effective immune
responses against infections and cancer. In the last 40 years, many receptors, their …

Tuning the threshold of natural killer cell responses

E Narni-Mancinelli, S Ugolini, E Vivier - Current opinion in immunology, 2013 - Elsevier
Natural killer cells are lymphocytes of the innate immune system that can kill an array of
tumor and infected cells and secrete cytokines that participate in the shaping of the adaptive …

Natural killer cells as an initial defense against pathogens

MB Lodoen, LL Lanier - Current opinion in immunology, 2006 - Elsevier
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse
range of pathogens. Recognition of infection by NK cells is accomplished by the activation of …

Natural killer cells regulate diverse T cell responses

SQ Crome, PA Lang, KS Lang, PS Ohashi - Trends in immunology, 2013 - cell.com
Natural killer (NK) cells are important mediators of the immune response against microbial
pathogens and tumors. There is growing evidence from mouse and human studies that, NK …

Cytokine regulation of natural killer cell effector functions

NW Zwirner, CI Domaica - Biofactors, 2010 - Wiley Online Library
Initially described as effectors of natural cytotoxicity and critical players for the control of viral
infections and tumor growth, recent investigations unraveled more widespread functions for …

NK cells regulating T cell responses: mechanisms and outcome

J Crouse, HC Xu, PA Lang, A Oxenius - Trends in immunology, 2015 - cell.com
Natural killer (NK) cells are important innate effectors in immunity. NK cells also have a role
in the regulation of the adaptive immune response, and have been shown, in different …

Natural killer cell responses to viral infection

JD Brandstadter, Y Yang - Journal of innate immunity, 2011 - karger.com
Natural killer (NK) cells, as part of the innate immune system, play a key role in host defense
against viral infections. Recent advances have indicated that NK cell activation and function …