Six-year follow-up of HIV-1-infected adults in a clinical trial of antiretroviral therapy with indinavir, zidovudine, and lamivudine

RM Gulick, A Meibohm, D Havlir, JJ Eron, A Mosley… - Aids, 2003 - journals.lww.com
Objective: To assess virological and immunological responses and toxicity in subjects
receiving combination antiretroviral therapy. Design: Six-year follow-up of a single arm of a …

Treatment with indinavir, zidovudine, and lamivudine in adults with human immunodeficiency virus infection and prior antiretroviral therapy

RM Gulick, JW Mellors, D Havlir, JJ Eron… - … England Journal of …, 1997 - Mass Medical Soc
Background The new protease inhibitors are potent inhibitors of the human
immunodeficiency virus (HIV), and in combination with other antiretroviral drugs they may be …

Virological and immunological effects of combination antiretroviral therapy with zidovudine, lamivudine, and indinavir during primary human immunodeficiency virus …

D Smith, MM Berrey, M Robertson… - The Journal of …, 2000 - academic.oup.com
Forty-seven patients presenting with primary human immunodeficiency virus (HIV) infection
were treated with zidovudine 200 mg 3 times a day, lamivudine 150 mg 2 times a day, and …

[HTML][HTML] A controlled trial of two nucleoside analogues plus indinavir in persons with human immunodeficiency virus infection and CD4 cell counts of 200 per cubic …

SM Hammer, KE Squires, MD Hughes… - … England Journal of …, 1997 - Mass Medical Soc
Background The efficacy and safety of adding a protease inhibitor to two nucleoside
analogues to treat human immunodeficiency virus type 1 (HIV-1) infection are not clear. We …

A randomized, controlled trial of indinavir, zidovudine, and lamivudine in adults with advanced human immunodeficiency virus type 1 infection and prior antiretroviral …

M Hirsch, R Steigbigel, S Staszewski… - The Journal of …, 1999 - academic.oup.com
A randomized, double-blind, multicenter study of indinavir, zidovudine, and lamivudine was
conducted in 320 adults with human immunodeficiency virus type 1 (HIV-1) infection,⩽ 50 …

Predictors of Virologic and Clinical Outcomes in HIV-1–Infected Patients Receiving Concurrent Treatment with Indinavir, Zidovudine, and Lamivudine: AIDS Clinical …

LM Demeter, MD Hughes, RW Coombs… - Annals of internal …, 2001 - acpjournals.org
Background: A substantial proportion of patients with HIV infection will not respond to
antiretroviral therapy. Early predictors of response to treatment are needed to identify …

[HTML][HTML] Maintenance antiretroviral therapies in HIV-infected subjects with undetectable plasma HIV RNA after triple-drug therapy

DV Havlir, IC Marschner, MS Hirsch… - … England Journal of …, 1998 - Mass Medical Soc
Background Combination antiretroviral therapy with indinavir, zidovudine, and lamivudine
can suppress the level of human immunodeficiency virus (HIV) RNA in plasma below the …

Correspondence between the effect of zidovudine plus lamivudine on plasma HIV level/CD4 lymphocyte count and the incidence of clinical disease in infected …

AN Phillips, J Eron, J Bartlett, DR Kuritzkes… - AIDS, 1997 - journals.lww.com
Objectives: To investigate whether apparently beneficial changes in plasma HIV RNA level
and CD4 lymphocyte count that are induced by antiretroviral therapy are associated with a …

Simultaneous vs sequential initiation of therapy with indinavir, zidovudine, and lamivudine for HIV-1 infection: 100-week follow-up

RM Gulick, JW Mellors, D Havlir, JJ Eron, C Gonzalez… - Jama, 1998 - jamanetwork.com
Context.—Combination antiretroviral therapy can markedly suppress human
immunodeficiency virus (HIV) replication but the duration of HIV suppression varies among …

Immunologic responses associated with 12 weeks of combination antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS Clinical …

MM Lederman, E Connick, A Landay… - Journal of Infectious …, 1998 - academic.oup.com
Abstract Human immunodeficiency virus (HIV)-1 infection is associated with progressive cell-
mediated immune deficiency and abnormal immune activation. Although highly active …