Hyaluronic acid in ocular drug delivery

X Zhang, D Wei, Y Xu, Q Zhu - Carbohydrate Polymers, 2021 - Elsevier
As a naturally-occurring polysaccharide which could be found in various ophthalmic tissues,
hyaluronic acid (HA) has a wide range of applications in the eye, including treatment of dry …

[HTML][HTML] Hyaluronic acid: Its versatile use in ocular drug delivery with a specific focus on hyaluronic acid-based polyelectrolyte complexes

S Casey-Power, R Ryan, G Behl, P McLoughlin… - Pharmaceutics, 2022 - mdpi.com
Extensive research is currently being conducted into novel ocular drug delivery systems
(ODDS) that are capable of surpassing the limitations associated with conventional …

Hyaluronic acid‐based nanocomposite hydrogels for ocular drug delivery applications

LK Widjaja, M Bora, PNPH Chan, V Lipik… - … Research Part A, 2014 - Wiley Online Library
Hyaluronic acid (HA) is a widely investigated biomaterial for many therapeutic applications
owing to its unique properties of biocompatibility, biodegradation, and viscoelasticity. HA …

[HTML][HTML] Polysaccharides in ocular drug delivery

N Dubashynskaya, D Poshina, S Raik, A Urtti… - Pharmaceutics, 2019 - mdpi.com
Polysaccharides, such as cellulose, hyaluronic acid, alginic acid, and chitosan, as well as
polysaccharide derivatives, have been successfully used to augment drug delivery in the …

An insight on hyaluronic acid in drug targeting and drug delivery

AK Yadav, P Mishra, GP Agrawal - Journal of drug targeting, 2008 - Taylor & Francis
Hyaluronic acid (HA) has recently been studied for its use in drug delivery applications.
Medically, HA is used as a surgical aid in ophthalmology. It also possesses therapeutic …

[HTML][HTML] Hydrogel biomaterials for application in ocular drug delivery

CR Lynch, PPD Kondiah, YE Choonara… - … in bioengineering and …, 2020 - frontiersin.org
There are many challenges involved in ocular drug delivery. These are a result of the many
tissue barriers and defense mechanisms that are present with the eye; such as the cornea …

Hyaluronate and its derivatives for customized biomedical applications

H Kim, H Jeong, S Han, S Beack, BW Hwang, M Shin… - Biomaterials, 2017 - Elsevier
Since hyaluronate (HA) was firstly isolated from the vitreous of bovine eyes in 1934, HA has
been widely investigated for various biomedical applications. As a naturally-occurring …

Insight on updates in polysaccharides for ocular drug delivery

NS Chandra, S Gorantla, S Priya, G Singhvi - Carbohydrate Polymers, 2022 - Elsevier
Ocular drug delivery is a significantly challenging task due to the presence of various
anatomical and physiological barriers in the eye. Naturally available polysaccharides, when …

Carbohydrate polymer-based bioadhesive formulations and their potentials for the treatment of ocular diseases: a review

X Tang, J Liu, R Yan, Q Peng - International Journal of Biological …, 2023 - Elsevier
Eyes are directly exposed to the outer environment and susceptible to infections, leading to
various ocular disorders. Local medication is preferred to treat eye diseases due to its …

Hyaluronic acid in drug delivery systems

YJ Jin, T Ubonvan, DD Kim - Journal of Pharmaceutical …, 2010 - koreascience.kr
Hyaluronic acid (HA) is a biodegradable, biocompatible, non-toxic, non-immunogenic and
non-inflammatory linear polysaccharide, which has been used for various medical …