A prospective controlled study was carried out in 60 consecutive cadaver renal donors
comparing cold storage to pulsatile machine-perfusion preservation. Each donor served as …

Ischemic injury to the renal allograft, prior to implantation, is an important cause of delayed
graft function. With improved understanding of the pathophysiological mechanisms involved …

Hypothermic preservation is known to cause renal graft injury, especially in donation after
circulatory death (DCD) kidney transplantation. We investigated the impact of cold storage …

Ex vivo normothermic perfusion (EVNP) technology is a promising means of organ
preservation, assessment, and preconditioning prior to kidney transplantation, which has …

Methods. Porcine kidneys were subjected to 10 min of warm ischemia followed by 18 hr of
static cold storage with hyperosomolar citrate (HOC), histidine-tryptophan-ketoglutarate …

Background. Better preservation strategies for the storage of donation after circulatory death
grafts are essential to improve graft function and to increase the kidney donor pool. We …

Background Donation after circulatory death (DCD) is current clinical practice to increase the
donor pool. Deleterious effects on renal graft function are described for hypothermic …

BACKGROUND: Restoring metabolism to an organ after hypothermic storage and before
transplantation could reverse some of the detrimental effects of ischemic injury. This may be …

Machine perfusion for preservation led to compelling success for the outcome of renal
transplantation. Further refinements of methods to decrease preservation injury remain an …

Kidney transplantation is the treatment of choice for end-stage renal disease. Despite its
superiority over dialysis, the persisting organ shortage remains a major drawback …