BACKGROUND: Polarization of macrophages by specific micro-environmental conditions
impacts upon their function following subsequent activation. This study aimed to …

Macrophages are highly plastic cells that can polarize into functionally distinct subsets in
vivo and in vitro in response to environmental signals. The development of protocols to …

Background Macrophages are a heterogeneous cell population which in response to the
cytokine milieu polarize in either classically activated macrophages (M1) or alternatively …

Monocytes/macrophages (MΦ), considered as plastic cells, can differentiate into either a pro-
inflammatory (M1) subtype, also known as a classically activated subtype, or an anti …

Macrophages are a heterogeneous population of innate myeloid cells involved in health and
disease, which are the most functionally diverse cells of the hematopoietic system. The main …

The mechanisms by which macrophages control the inflammatory response, wound healing,
biomaterial-interactions, and tissue regeneration appear to be related to their activation …

Macrophage polarization is increasingly recognised as an important pathogenetic factor in
inflammatory and neoplastic diseases. Proinflammatory M1 macrophages promote T helper …

Macrophages are key inflammatory immune cells that display dynamic phenotypes and
functions in response to their local microenvironment. Major advances have occurred in …

Macrophages (Mφ) undergo activation to pro-inflammatory (M1) or anti-inflammatory (M2)
phenotypes in response to pathophysiologic stimuli and dysregulation of the M1-M2 balance …

Macrophages form a heterogeneous cell population displaying multiple functions, and can
be polarized into pro-(M1) or anti-inflammatory (M2) macrophages, by environmental factors …