Expression of newly identified secretory CEACAM1a isoforms in the intestinal epithelium

K Terahara, M Yoshida, F Taguchi, O Igarashi… - Biochemical and …, 2009 - Elsevier
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) regulates
intestinal immunological homeostasis. However, precise expression patterns of CEACAM1 …

The short isoform of the CEACAM1 receptor in intestinal T cells regulates mucosal immunity and homeostasis via Tfh cell induction

L Chen, Z Chen, K Baker, EM Halvorsen, AP da Cunha… - Immunity, 2012 - cell.com
Carcinoembryonic antigen cell adhesion molecule like I (CEACAM1) is expressed on
activated T cells and signals through either a long (L) cytoplasmic tail containing immune …

Ceacam1a−/− Mice Are Completely Resistant to Infection by Murine Coronavirus Mouse Hepatitis Virus A59

E Hemmila, C Turbide, M Olson, S Jothy… - Journal of …, 2004 - Am Soc Microbiol
ABSTRACT CEACAM1a glycoproteins are members of the immunoglobulin (Ig) superfamily
and the carcinoembryonic antigen family. Isoforms expressing either two or four alternatively …

The transmembrane domain of CEACAM1-4S is a determinant of anchorage independent growth and tumorigenicity

EL Lawson, DR Mills, KE Brilliant, DC Hixson - PLoS One, 2012 - journals.plos.org
CEACAM1 is a multifunctional Ig-like cell adhesion molecule expressed by epithelial cells in
many organs. CEACAM1-4L and CEACAM1-4S, two isoforms produced by differential …

Re‐expression of CEACAM1 long cytoplasmic domain isoform is associated with invasion and migration of colorectal cancer

J Ieda, S Yokoyama, K Tamura… - … journal of cancer, 2011 - Wiley Online Library
Carcinoembryonic antigen‐related cell adhesion molecule 1 (CEACAM1) is known to be
downregulated at the transcriptional level in adenoma and carcinoma. Recent reports have …

CEACAM1 specifically suppresses B cell receptor signaling-mediated activation

N Tsugawa, D Yamada, T Watabe, M Onizawa… - Biochemical and …, 2021 - Elsevier
Carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1) expressed in T
cells may regulate immune responses in the gut. In addition to T cells, B cells are also an …

Host-related carcinoembryonic antigen cell adhesion molecule 1 promotes metastasis of colorectal cancer

A Arabzadeh, C Chan, AL Nouvion, V Breton… - Oncogene, 2013 - nature.com
Liver metastasis is the predominant cause of colorectal cancer (CRC)-related mortality in
developed countries. Carcinoembryonic antigen-related cell adhesion molecule 1 …

CEACAM1 as a central modulator of metabolism, tumor progression, angiogenesis and immunity

AL Nouvion, N Beauchemin - Medecine Sciences: M/S, 2009 - europepmc.org
CEACAM1 (carcinoembryonic antigen cell adhesion molecule 1), a member of the
immunoglobulin (Ig) superfamily, is a heavily glycosylated protein. This glycoprotein exhibits …

Secreted CEACAM1 splice variants in rat cell lines and in vivo in rat serum

M Budt, B Michely, MM Müller, W Reutter… - … and biophysical research …, 2002 - Elsevier
The widely expressed adhesion receptor CEACAM1 is a member of the carcinoembryonic
antigen (CEA) family within the immunoglobulin (Ig) superfamily of glycoproteins. While the …

Novel protein isoforms of carcinoembryonic antigen are secreted from pancreatic, gastric and colorectal cancer cells

K Hatakeyama, K Wakabayashi-Nakao, K Ohshima… - BMC research …, 2013 - Springer
Background Carcinoembryonic antigen-related cell adhesion molecule 5 (CEACAM5) is an
oncofetal cell surface glycoprotein. Because of its high expression in cancer cells and …