First experience with heterotopic thoracic pig‐to‐baboon cardiac xenotransplantation
A Bauer, J Postrach, M Thormann, S Blanck… - …, 2010 - Wiley Online Library
Bauer A, Postrach J, Thormann M, Blanck S, Faber C, Wintersperger B, Michel S, Abicht J‐
M, Christ F, Schmitz C, Schmoeckel M, Reichart B, Brenner P. First experience with …
M, Christ F, Schmitz C, Schmoeckel M, Reichart B, Brenner P. First experience with …
[HTML][HTML] Cardiac xenotransplantation: recent preclinical progress with 3-month median survival
CGA McGregor, WR Davies, K Oi, SS Teotia… - The Journal of thoracic …, 2005 - Elsevier
OBJECTIVES: Transplantation is limited by a lack of human organ donors. Organs derived
from animals, most likely the pig, represent a potential solution to this problem. For the heart …
from animals, most likely the pig, represent a potential solution to this problem. For the heart …
Heart xenotransplantation in primate models
J Postrach, A Bauer, M Schmoeckel, B Reichart… - … : Methods and Protocols, 2012 - Springer
Xenotransplantation is a potential solution for the worldwide persisting donor organ
shortage. However, immunological and physiological barriers need to be overcome before …
shortage. However, immunological and physiological barriers need to be overcome before …
[HTML][HTML] Current status of pig heart xenotransplantation
MM Mohiuddin, B Reichart, GW Byrne… - International Journal of …, 2015 - Elsevier
Significant progress in understanding and overcoming cardiac xenograft rejection using a
clinically relevant large animal pig-to-baboon model has accelerated in recent years. This …
clinically relevant large animal pig-to-baboon model has accelerated in recent years. This …
Heart xenotransplantation: historical background, experimental progress, and clinical prospects
If pig hearts could be transplanted successfully into patients with end-stage cardiac failure,
the critical shortage of hearts from deceased human donors would be overcome. The …
the critical shortage of hearts from deceased human donors would be overcome. The …
A standardized approach to orthotopic (life-supporting) porcine cardiac xenotransplantation in a nonhuman primate model
CE Goerlich, BP Griffith, A Shah, JA Treffalls… - …, 2023 - journals.lww.com
Cardiac xenotransplantation from swine has been proposed to “bridge the gap” in supply for
heart failure patients requiring transplantation. Recent preclinical success using genetically …
heart failure patients requiring transplantation. Recent preclinical success using genetically …
Hemodynamics in pig‐to‐baboon heterotopic thoracic cardiac xenotransplantation: Recovery from perioperative cardiac xenograft dysfunction and impairment by …
M Bender, A Panelli, B Reichart, J Radan… - …, 2024 - Wiley Online Library
Introduction Orthotopic cardiac xenotransplantation has seen notable improvement, leading
to the first compassionate use in 2022. However, it remains challenging to define the clinical …
to the first compassionate use in 2022. However, it remains challenging to define the clinical …
Cardiac xenotransplantation: from concept to clinic
B Reichart, DKC Cooper, M Längin… - Cardiovascular …, 2022 - academic.oup.com
For many patients with terminal/advanced cardiac failure, heart transplantation is the most
effective, durable treatment option, and offers the best prospects for a high quality of life. The …
effective, durable treatment option, and offers the best prospects for a high quality of life. The …
Cardiac xenotransplantation: progress toward the clinic
CGA McGregor, SS Teotia, GW Byrne… - …, 2004 - journals.lww.com
Background. Animal organs could satisfy the demand for solid organ transplants, which
currently exceeds the limited human donor supply. Hyperacute rejection, the initial immune …
currently exceeds the limited human donor supply. Hyperacute rejection, the initial immune …
Seven years of experiences of preclinical experiments of xeno-heart transplantation of pig to non-human primate (cynomolgus monkey)
SJ Lee, JS Kim, HK Chee, IJ Yun, KS Park… - Transplantation …, 2018 - Elsevier
Background The absolute shortage of donors compared with patients requiring
transplantation is currently an unsolved problem, and the only possible solution may be …
transplantation is currently an unsolved problem, and the only possible solution may be …