Exploration of the Correlation Between GRHL1 Expression and Tumor Microenvironment in Endometrial Cancer and Immunotherapy
S Guo, W Bai, F Cui, X Chen, X Fang… - Pharmacogenomics …, 2024 - Taylor & Francis
Introduction GRHL1 belongs to the family of Grainyhead-like (GRHL). Previous studies have
shown that dysregulation of growth and survival pathways is associated with the GRHL …
shown that dysregulation of growth and survival pathways is associated with the GRHL …
GRHL2 expression functions in breast cancer aggressiveness and could serve as prognostic and diagnostic biomarker for breast cancer
X Bai, Y Li, Y Li, F Li, N Che, C Ni… - Clinical Medicine …, 2022 - journals.sagepub.com
Background: Breast cancer (BC) is the most frequent malignancy in women worldwide and
the leading cause of female cancer–associated death in the world. Grainyhead-like 2 …
the leading cause of female cancer–associated death in the world. Grainyhead-like 2 …
GRHL2 is a candidate prognostic and immunotherapy biomarker in breast cancer
X Bai, Y Li, Y Li, F Li, N Che, C Ni, N Zhao, X Zhao… - 2021 - researchsquare.com
Background: Breast cancer (BC) is the most frequent malignancy in women worldwide and
the leading cause of female cancer‐associated death in the world. Thus, we need to identify …
the leading cause of female cancer‐associated death in the world. Thus, we need to identify …
[HTML][HTML] Experimental and clinical evidence suggests that GRPEL2 plays an oncogenic role in HCC development
MC Lai, QQ Zhu, J Xu, WJ Zhang - American journal of cancer …, 2021 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) continues to cause severe burden worldwide. The limited
options especially toward HCC with metastasis prompts us to identify novel molecules for …
options especially toward HCC with metastasis prompts us to identify novel molecules for …
Expression of transcription factor grainyhead-like-2 in breast cancer tissues and its relationship with clinicopathological features and prognosis of patients
F WANG, M WEI, L YANG, W MA… - Chinese Journal of …, 2019 - pesquisa.bvsalud.org
Objective: To detect the expression of GRHL2 (grainyhead-like-2) in breast cancer tissues
and to explore its correlation with clinicopathological characteristics and prognosis of breast …
and to explore its correlation with clinicopathological characteristics and prognosis of breast …
GRHL3 promotes tumor growth and metastasis via the MEK pathway in colorectal cancer
L Tan, W Qu, D Wu, M Liu, Q Wang, Q Ai… - Analytical Cellular …, 2021 - Wiley Online Library
GRHL3 is a factor associated with a tumor, of which the molecular mechanism remains a
further investigation. We explored the underlying mechanism of tumor‐promoting effect of …
further investigation. We explored the underlying mechanism of tumor‐promoting effect of …
GRHL2 upregulation predicts a poor prognosis and promotes the resistance of serous ovarian cancer to cisplatin
Y Nie, Y Ding, M Yang - OncoTargets and therapy, 2020 - Taylor & Francis
Background GRHL2 has been shown to function in ovarian carcinogenesis. However, the
relationship between GRHL2 and cisplatin (DDP) resistance in serous ovarian cancer (SOC) …
relationship between GRHL2 and cisplatin (DDP) resistance in serous ovarian cancer (SOC) …
[HTML][HTML] Grainyhead-like 2 promotes tumor growth and is associated with poor prognosis in colorectal cancer
Y Quan, M Xu, P Cui, M Ye, B Zhuang, Z Min - Journal of Cancer, 2015 - ncbi.nlm.nih.gov
GRHL2 was implicated in regulating cancer development. Our previous study demonstrated
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
that knockdown GRHL2 in colorectal cancer (CRC) cells inhibited cell proliferation by …
Knockdown of GRHL2 inhibited proliferation and induced apoptosis of colorectal cancer by suppressing the PI3K/Akt pathway
F Hu, Z He, C Sun, D Rong - Gene, 2019 - Elsevier
Abstract Grainyhead-like 2 (GRHL2) transcription factor is implicated in many types of
cancers. However, the role of GRHL2 in colorectal cancer (CRC) has not been fully …
cancers. However, the role of GRHL2 in colorectal cancer (CRC) has not been fully …
Clinical implications of GRHL3 protein expression in breast cancer
H Xu, C Liu, Z Zhao, N Gao, G Chen, Y Wang, J Cui - Tumor Biology, 2014 - Springer
The objective of this study was to investigate the expression and significance of the GRHL3
protein in breast cancer diagnosis and prognosis. Overall, 111 patients with histologically …
protein in breast cancer diagnosis and prognosis. Overall, 111 patients with histologically …