Effect of LGR4/EGFR signaling on cell growth and cancer stem cell-like characteristics in liver cancer

Y Liu, Y Zhang, S Chen, X Zhong, Q Liu - Cytokine, 2023 - Elsevier
Purpose Hepatocellular carcinoma (HCC) is the most common primary liver cancer. Leucine-
rich repeat containing G-protein-coupled receptors 4 (LGR4) participates in tumor …

HMGA1 facilitates tumor progression through regulating Wnt/β-catenin pathway in endometrial cancer

X Han, Y Cao, K Wang, G Zhu - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Recent studies have identified a unique role for high mobility group protein A1 (HMGA1) as
a major regulator of tumor progression and in diverse tumor models. Emerging evidences …

[HTML][HTML] A comprehensive analysis of potential gastric cancer prognostic biomarker ITGBL1 associated with immune infiltration and epithelial–mesenchymal transition

Z Wang, L Fu, J Zhang, Y Ge, C Guo, R Wang… - BioMedical Engineering …, 2022 - Springer
Abstract Background Integrin, beta-like 1 (ITGBL1) is involved in a variety of human
malignancies. However, the information on the involvement of ITGBL1 in gastric carcinoma …

GOLPH3 induces epithelial–mesenchymal transition via Wnt/β‐catenin signaling pathway in epithelial ovarian cancer

J Sun, X Yang, R Zhang, S Liu, X Gan, X Xi… - Cancer …, 2017 - Wiley Online Library
Abstract Golgi phosphoprotein 3 (GOLPH 3), a newly recognized oncogene, is associated
with tumor growth, metastasis, and poor prognosis in several types of cancer. However, its …

Comprehensive Analysis of Glutamate‐Rich WD Repeat‐Containing Protein 1 and Its Potential Clinical Significance for Pancancer

Y Wu, X Wu, Y Li, W Zhao, Y Yue, B Wu… - BioMed Research …, 2021 - Wiley Online Library
Background and Objective. Glutamate‐rich WD repeat‐containing protein 1 (GRWD1), as a
novel CDT1‐binding protein, plays a critical role in the initial stage of DNA replication. To …

[HTML][HTML] Plasma gelsolin confers chemoresistance in ovarian cancer by resetting the relative abundance and function of macrophage subtypes

M Asare-Werehene, H Tsuyoshi, H Zhang, R Salehi… - Cancers, 2022 - mdpi.com
Simple Summary Ovarian cancer is one of the deadliest female cancers with very poor
survival, primarily due to late diagnosis, recurrence and chemoresistance. Although the over …

[HTML][HTML] Analysis of ARHGAP4 expression with colorectal cancer clinical characteristics and prognosis

M Fu, S Pan, X Cai, Y Hu, W Zhang, Q Pan - Frontiers in oncology, 2022 - frontiersin.org
Background This study aims to analyze the correlation between ARHGAP4 in the expression
and clinical characteristics of colorectal cancer (CRC), and the influence of ARHGAP4 …

[HTML][HTML] Integrated multi-omics analysis and machine learning identify hub genes and potential mechanisms of resistance to immunotherapy in gastric cancer

J Wang, J Feng, X Chen, Y Weng, T Wang… - Aging (Albany …, 2024 - ncbi.nlm.nih.gov
Background: Patients with gastric cancer respond poorly to immunotherapy. There are still
unknowns about the biomarkers associated with immunotherapy sensitivity and their …

[HTML][HTML] GRAM domain-containing protein 1A (GRAMD1A) promotes the expansion of hepatocellular carcinoma stem cell and hepatocellular carcinoma growth …

B Fu, W Meng, H Zhao, B Zhang, H Tang, Y Zou… - Scientific reports, 2016 - nature.com
Hepatocellular carcinoma (HCC) is the leading cause for cancer death worldwide, new
prognostic factors and targets are critical for HCC treatment. Here, we found GRAMD1A was …

Overexpression of GRP78 is associated with malignant transformation in epithelial ovarian tumors

LW Huang, CY Lin, CC Lee, TZ Liu… - … & Molecular Morphology, 2012 - journals.lww.com
Aim: Glucose-regulated protein 78 (GRP78) is one of the best-characterized endoplasmic
reticulum chaperone proteins. The aim of this study was to explore the potential implications …