Next-generation stem cells—ushering in a new era of cell-based therapies
EA Kimbrel, R Lanza - Nature Reviews Drug Discovery, 2020 - nature.com
Naturally occurring stem cells isolated from humans have been used therapeutically for
decades. This has primarily involved the transplantation of primary cells such as …
decades. This has primarily involved the transplantation of primary cells such as …
Stem cells: A revolution in therapeutics—Recent advances in stem cell biology and their therapeutic applications in regenerative medicine and cancer therapies
M Mimeault, R Hauke, SK Batra - Clinical Pharmacology & …, 2007 - Wiley Online Library
Basic and clinical research accomplished during the last few years on embryonic, fetal,
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …
amniotic, umbilical cord blood, and adult stem cells has constituted a revolution in …
Emerging use of stem cells in regenerative medicine
Stem cells represent a unique opportunity for regenerative medicine to cure a broad number
of diseases for which current treatment only alleviates symptoms or retards further disease …
of diseases for which current treatment only alleviates symptoms or retards further disease …
Stem cell platforms for regenerative medicine
TJ Nelson, A Behfar, S Yamada… - Clinical and …, 2009 - Wiley Online Library
The pandemic of chronic degenerative diseases associated with aging demographics
mandates development of effective approaches for tissue repair. As diverse stem cells …
mandates development of effective approaches for tissue repair. As diverse stem cells …
Engineering the next generation of cell-based therapeutics
Cell-based therapeutics are an emerging modality with the potential to treat many currently
intractable diseases through uniquely powerful modes of action. Despite notable recent …
intractable diseases through uniquely powerful modes of action. Despite notable recent …
Advances in stem cell research and therapeutic development
Despite many reports of putative stem-cell-based treatments in genetic and degenerative
disorders or severe injuries, the number of proven stem cell therapies has remained small …
disorders or severe injuries, the number of proven stem cell therapies has remained small …
Prospects for stem cell-based therapy
GQ Daley, DT Scadden - Cell, 2008 - cell.com
Resident pools of somatic stem cells in many organs are responsible for tissue maintenance
and repair. The goal of regenerative medicine is to exploit these cells either by transplanting …
and repair. The goal of regenerative medicine is to exploit these cells either by transplanting …
The therapeutic potential of stem cells
FM Watt, RR Driskell - … of the Royal Society B: Biological …, 2010 - royalsocietypublishing.org
In recent years, there has been an explosion of interest in stem cells, not just within the
scientific and medical communities but also among politicians, religious groups and …
scientific and medical communities but also among politicians, religious groups and …
Stem cells in drug discovery, tissue engineering, and regenerative medicine: emerging opportunities and challenges
VS Nirmalanandhan… - Journal of biomolecular …, 2009 - journals.sagepub.com
Stem cells, irrespective of their origin, have emerged as valuable reagents or tools in human
health in the past 2 decades. Initially, a research tool to study fundamental aspects of …
health in the past 2 decades. Initially, a research tool to study fundamental aspects of …
Large scale production of stem cells and their derivatives
R Zweigerdt - Engineering of Stem Cells, 2009 - Springer
Stem cells have been envisioned to become an unlimited cell source for regenerative
medicine. Notably, the interest in stem cells lies beyond direct therapeutic applications. They …
medicine. Notably, the interest in stem cells lies beyond direct therapeutic applications. They …