Protein biomarkers for traumatic and ischemic brain injury: from bench to bedside

Z Zhang, S Mondello, F Kobeissy, R Rubenstein… - Translational Stroke …, 2011 - Springer
Stroke is the second leading cause of death worldwide and the third leading cause of death
in the USA. A clinically useful biomarker for the diagnosis of stroke does not currently exist …

Blood biomarkers in moderate-to-severe traumatic brain injury: potential utility of a multi-marker approach in characterizing outcome

AP Di Battista, JE Buonora, SG Rhind… - Frontiers in …, 2015 - frontiersin.org
Background Blood biomarkers are valuable tools for elucidating complex cellular and
molecular mechanisms underlying traumatic brain injury (TBI). Profiling distinct classes of …

MicroRNA signature of traumatic brain injury: from the biomarker discovery to the point-of-care

V Di Pietro, KM Yakoub, U Scarpa, C Di Pietro… - Frontiers in …, 2018 - frontiersin.org
Traumatic brain injury (TBI) is a serious problem that causes high morbidity and mortality
around the world. Currently, no reliable biomarkers are used to assess the severity and …

[引用][C] Brain Injury Biomarkers and Their Utilities in Personalized Medicine

KKW Wang, RL Hayes - Asia-Pacific Biotech. News, 2011

One-year prospective study of plasma biomarkers from CNS in patients with mild traumatic brain injury

GJB Clarke, T Skandsen, H Zetterberg… - Frontiers in …, 2021 - frontiersin.org
Objective: To investigate the longitudinal evolution of three blood biomarkers: neurofilament
light (NFL), glial fibrillary acidic protein (GFAP) and tau, in out-patients and hospitalized …

A novel blood inflammatory indicator for predicting deterioration risk of mild traumatic brain injury

X Ge, L Zhu, M Li, W Li, F Chen, Y Li… - Frontiers in aging …, 2022 - frontiersin.org
Mild traumatic brain injury (mTBI) has a relatively higher incidence in aging people due to
walking problems. Cranial computed tomography and magnetic resonance imaging provide …

Neuroanatomical zones of human traumatic brain injury reveal significant differences in protein profile and protein oxidation: Implications for secondary injury events

N Gowthami, N Pursotham, G Dey… - Journal of …, 2023 - Wiley Online Library
Traumatic brain injury (TBI) causes significant neurological deficits and long‐term
degenerative changes. Primary injury in TBI entails distinct neuroanatomical zones, ie …

Predictive biomarkers of recovery in traumatic brain injury

S Giacoppo, P Bramanti, M Barresi, D Celi… - Neurocritical care, 2012 - Springer
Recent advances in medicine, intensive care and diagnostic imaging modalities have led to
a pronounced reduction in deaths and disability resulting from traumatic brain injury …

Protein biomarkers in traumatic brain injury: an omics approach

A Boutte, F Kobeissy, KK Wang… - Biomarkers of brain …, 2014 - api.taylorfrancis.com
Traumatic brain injuries (TBIs) pose a great health concern. In the United States alone,
nearly 2 million people per year will have suffered a TBI. In the civilian population, most TBIs …

A model for mild traumatic brain injury that induces limited transient memory impairment and increased levels of axon related serum biomarkers

E Rostami, J Davidsson, KC Ng, J Lu, A Gyorgy… - Frontiers in …, 2012 - frontiersin.org
Mild traumatic brain injury (mTBI) is one of the most common neuronal insults and can lead
to long-term disabilities. mTBI occurs when the head is exposed to a rapid acceleration …