Between GERD and NERD: the relevance of weakly acidic reflux

N de Bortoli, A Ottonello, F Zerbib… - Annals of the New …, 2016 - Wiley Online Library
Nonerosive reflux disease (NERD) is a common condition and the most frequent phenotype
of gastroesophageal reflux disease (GERD). NERD is extremely heterogeneous and …

NERD: an umbrella term including heterogeneous subpopulations

E Savarino, P Zentilin, V Savarino - Nature reviews Gastroenterology & …, 2013 - nature.com
Nonerosive reflux disease (NERD) represents the more common phenotypic presentation of
GERD and comprises patients who have typical symptoms without any mucosal breaks at …

Non‐erosive reflux disease, functional heartburn and gastroesophageal reflux disease; insights into pathophysiology and clinical presentation

EMM Quigley - Chinese journal of digestive diseases, 2006 - Wiley Online Library
Non‐erosive reflux disease (NERD) has emerged as a real entity in the spectrum of
gastroesophageal reflux disease (GERD) and may, indeed, represent the most common …

Nonerosive reflux disease: a pathophysiologic perspective

JD Long, RC Orlando - Current gastroenterology reports, 2008 - Springer
Nonerosive reflux disease (NERD) is the most common phenotype of gastroesophageal
reflux disease. By definition, patients with NERD have typical reflux symptoms caused by the …

Impedance-pH reflux patterns can differentiate non-erosive reflux disease from functional heartburn patients

E Savarino, P Zentilin, R Tutuian, D Pohl… - Journal of …, 2012 - Springer
Introduction Symptom association is important to distinguish non-erosive reflux disease
[NERD; abnormal oesophageal acid exposure time (AET) and/or positive symptom …

[HTML][HTML] Role of non-acid reflux in patients with non-erosive reflux disease

GP Karamanolis, R Tutuian - … Publication of the Hellenic Society of …, 2013 - ncbi.nlm.nih.gov
Non-erosive reflux disease (NERD) is the most common presentation of gastroesophageal
reflux disease. Although acid reflux is the most important cause of symptom generation in …

[HTML][HTML] Distinction between patients with non-erosive reflux disease and functional heartburn

M Giacchino, V Savarino, E Savarino - Annals of gastroenterology …, 2013 - ncbi.nlm.nih.gov
Non-erosive reflux disease (NERD) and functional heartburn (FH) are two different clinical
entities and the clear distinction between the two forms is actually possible thanks to the use …

Current advances in the diagnosis and treatment of nonerosive reflux disease

CL Chen, PI Hsu - Gastroenterology research and practice, 2013 - Wiley Online Library
Nonerosive reflux disease (NERD) is a distinct pattern of gastroesophageal reflux disease
(GERD). It is defined as a subcategory of GERD characterized by troublesome reflux‐related …

Functional heartburn has more in common with functional dyspepsia than with non-erosive reflux disease

E Savarino, D Pohl, P Zentilin, P Dulbecco, G Sammito… - Gut, 2009 - gut.bmj.com
Introduction: Functional dyspepsia and non-erosive reflux disease (NERD) are prevalent
gastrointestinal conditions with accumulating evidence regarding an overlap between the …

[HTML][HTML] Critical appraisal of Rome IV criteria: hypersensitive esophagus does belong to gastroesophageal reflux disease spectrum

L Frazzoni, M Frazzoni, N De Bortoli… - Annals of …, 2018 - ncbi.nlm.nih.gov
Abstract The Rome IV Committee introduced a major change in the classification of
functional gastrointestinal disorders, proposing a more restrictive definition of …