Esophageal symptoms can arise from gastroesophageal reflux disease (GERD) as well as
other mucosal and motor processes, structural disease, and functional esophageal …

NERD is common and its definition continues to evolve. For the present, however, this
should be considered to be heartburn with and without regurgitation due to …

Over the last several decades, the incidences of gastric cancer and peptic ulcer have
declined while the incidences of gastro-oesophageal reflux disease (GORD) and functional …

Background By analysis of symptom‐reflux association, endoscopy‐negative refractory
heartburn can be related to acid/non‐acid refluxes with impedance‐pH monitoring …

INTRODUCTION: Functional heartburn is defined by Rome III criteria as an endoscopy-
negative condition with normal oesophageal acid exposure time, negative symptom …

Most individuals with symptoms compatible with gastro-oesophageal reflux disease (GERD)
who undergo endoscopy will not show evidence of erosive oesophagitis. Indeed, it is now …

Background & aims Oesophageal acidification induces dyspeptic symptoms in healthy
individuals. This study aimed to evaluate the correlation between oesophageal acid …

Heartburn is the most specific symptom of gastroesophageal reflux disease (GERD). In
clinical practice, heartburn relief by a proton pump inhibitor (PPI) trial does suffice to confirm …

Abstract Background and Aim: The reason that some reflux episodes evoke symptoms is
poorly understood, therefore the aim of this study is to assess the determinants of reflux …

Gastroesophageal reflux disease (GERD) is a complex disorder with heterogeneous
symptoms and a multifaceted pathogenetic basis, which prevent a simple diagnostic …