Distinct clinical characteristics between patients with nonerosive reflux disease and those with reflux esophagitis

JCY Wu, CMY Cheung, VWS Wong… - Clinical Gastroenterology …, 2007 - Elsevier
Background & Aims: It has been postulated that nonerosive reflux disease (NERD) and
erosive reflux disease (ERD) are 2 distinct entities of gastroesophageal reflux disease. The …

The role of nonacid reflux in NERD: lessons learned from impedance-pH monitoring in 150 patients off therapy

E Savarino, P Zentilin, R Tutuian, D Pohl… - Official journal of the …, 2008 - journals.lww.com
METHODS Patients with typical reflux symptoms (heartburn and/or regurgitation) and normal
endoscopy (NERD) underwent a combined impedance-pH monitoring off proton pump …

the role of acid suppression in patients with non‐erosive reflux disease or functional heartburn

KR DeVault - Alimentary Pharmacology & Therapeutics, 2006 - Wiley Online Library
When patients with the typical reflux symptoms of heartburn, regurgitation, or both, undergo
endoscopy, up to 75% will not have endoscopic oesophagitis or evidence of Barrett's …

complete gastro‐oesophageal reflux monitoring–combined pH and impedance

R Tutuian, DO Castell - Alimentary pharmacology & …, 2006 - Wiley Online Library
Gastroesophagel reflux disease (GERD) is a common condition encountered in clinical
practice. Over the years there has been a continuous interaction between the understanding …

Pathophysiology, diagnosis, and pharmacological treatment of gastro-esophageal reflux disease

V Savarino, E Marabotto, P Zentilin… - Expert review of …, 2020 - Taylor & Francis
Introduction Gastro-esophageal reflux disease (GERD) is a highly prevalent, chronic,
relapsing disorder, whose knowledge has increased in last years thanks to the advent of …

Diagnosis of symptomatic gastroesophageal reflux disease

PJ Kahrilas - Official journal of the American College of …, 2003 - journals.lww.com
Gastroesophageal reflux disease (GERD) encompasses a heterogeneous group of patients
with differences in sensitivity to esophageal acid exposure, perception of pain, and …

Acid and non-acid reflux in Japanese patients with non-erosive reflux disease with persistent reflux symptoms, despite taking a double-dose of proton pump inhibitor …

K Iwakiri, N Kawami, H Sano, Y Tanaka… - Journal of …, 2009 - Springer
Background Combined multi-channel intra-luminal impedance and pH (Mll-pH) monitoring
can detect gastro-esophageal reflux and identify acid and non-acid reflux (NAR) events. It …

[PDF][PDF] Nonerosive reflux disease (NERD)-an update

T Hershcovici, R Fass - Journal of neurogastroenterology …, 2010 - synapse.koreamed.org
It has been demonstrated that 44% of the US population report gastroesophageal reflux
disease (GERD)-related symptoms at least once a month and 20% once a week. 1, 2 …

Categorization of patients with reflux symptoms referred for pH and impedance testing while off therapy

FKF Cheng, DM Albert, CL Maydonovitch… - Clinical …, 2015 - Elsevier
Background & Aims Patients with suspected gastroesophageal reflux disease (GERD) often
are treated empirically with proton pump inhibitors (PPIs). Patients whose symptoms are not …

Proximal reflux frequency not correlated with atypical gastroesophageal reflux disease (GERD) symptoms

K Liu, J Evans, S Clayton - Diseases of the Esophagus, 2023 - academic.oup.com
Though most known for heartburn and regurgitation, gastroesophageal reflux disease
(GERD) is attributed to countless atypical, extra-esophageal (EE) manifestations like cough …