Early cleavages influence the molecular and the metabolic pattern of individually cultured bovine blastocysts
MP Milazzotto, MD Goissis, JL Chitwood… - Molecular …, 2016 - Wiley Online Library
Embryo morphokinetics suggests that the timing of the first embryonic cell divisions may
predict the developmental potential of an embryo; however, correlations between embryonic …
predict the developmental potential of an embryo; however, correlations between embryonic …
Association between the morphokinetics of in-vitro-derived bovine embryos and the transcriptomic profile of the derived blastocysts
The time-lapse system is a non-invasive method that enables a continuous evaluation
through embryo development. Here, we examined the association between the …
through embryo development. Here, we examined the association between the …
Differential gene expression and developmental competence in in vitro produced bovine embryos
P Ripamonte, LG Mesquita, SS Cortezzi… - Zygote, 2012 - cambridge.org
The embryonic developmental block occurs at the 8-cell stage in cattle and is characterized
by a lengthening of the cell cycle and an increased number of embryos that stop …
by a lengthening of the cell cycle and an increased number of embryos that stop …
Seasonal variation in the morphokinetics of in-vitro-derived bovine embryos is associated with the blastocyst developmental competence and gene expression
Summer heat stress is a major cause of reduced development of preimplantation embryos.
Nevertheless, seasonal effects on embryo morphokinetics have been less studied. We used …
Nevertheless, seasonal effects on embryo morphokinetics have been less studied. We used …
[HTML][HTML] Overview of the transcriptomic landscape in bovine blastocysts and elongated conceptuses driving developmental competence
MB Rabaglino - animal, 2023 - Elsevier
In cattle, pregnancy loss due to early embryonic mortality is a major concern that significantly
impacts reproductive efficiency. Given the economic importance of cattle in livestock …
impacts reproductive efficiency. Given the economic importance of cattle in livestock …
Developmental kinetics of cleavage stage mouse embryos are related to their subsequent carbohydrate and amino acid utilization at the blastocyst stage
YSL Lee, GA Thouas, DK Gardner - Human reproduction, 2015 - academic.oup.com
STUDY QUESTION What is the relationship between cleavage stage embryo kinetics,
blastocyst metabolism and subsequent embryo viability? SUMMARY ANSWER Embryos …
blastocyst metabolism and subsequent embryo viability? SUMMARY ANSWER Embryos …
Metabolism-epigenetic interactions on in vitro produced embryos
MP Milazzotto, J Ispada… - Reproduction, Fertility and …, 2022 - CSIRO Publishing
Metabolism and epigenetics, which reciprocally regulate each other in different cell types,
are fundamental aspects of cellular adaptation to the environment. Evidence in cancer and …
are fundamental aspects of cellular adaptation to the environment. Evidence in cancer and …
Differential gene expression profile in bovine blastocysts resulting from hyperglycemia exposure during early cleavage stages
GLM Cagnone, I Dufort, C Vigneault… - Biology of …, 2012 - academic.oup.com
To understand the compromised survival of embryos derived from assisted reproductive
techniques, transcriptome survey of early embryonic development has shown the impact of …
techniques, transcriptome survey of early embryonic development has shown the impact of …
Single-cell RNA sequencing reveals developmental heterogeneity of blastomeres during major genome activation in bovine embryos
I Lavagi, S Krebs, K Simmet, A Beck… - Scientific reports, 2018 - nature.com
Embryonic development is initially controlled by maternal RNAs and proteins stored in the
oocyte, until gene products gradually generated by the embryo itself take over. Major …
oocyte, until gene products gradually generated by the embryo itself take over. Major …
Rapidly cleaving bovine two‐cell embryos have better developmental potential and a distinctive mRNA pattern
E Orozco‐Lucero, I Dufort, C Robert… - Molecular …, 2014 - Wiley Online Library
Mammalian embryos that rapidly reach the two‐cell stage in culture have a higher
probability of becoming viable blastocysts. Our goal was to separate two‐cell bovine …
probability of becoming viable blastocysts. Our goal was to separate two‐cell bovine …
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