First-generation antipsychotic long-acting injections v. oral antipsychotics in schizophrenia: systematic review of randomised controlled trials and observational studies

PM Haddad, M Taylor, OS Niaz - The British Journal of Psychiatry, 2009 - cambridge.org
BackgroundAntipsychotic long-acting injections (LAIs) are often used in an attempt to
improve medication adherence in people with schizophrenia. AimsTo compare first …

A further consideration on long-acting injectable versus oral antipsychotics in the treatment of schizophrenia: a narrative review and critical appraisal

T Suzuki - Expert opinion on drug delivery, 2016 - Taylor & Francis
Introduction: Many patients with schizophrenia exhibit difficulties in maintaining adherence
to oral antipsychotics, calling for more reliable drug delivery systems. Areas covered: While …

Comparison of long-acting antipsychotic injection and oral antipsychotics in schizophrenia

JM Olivares, B Pinal, C Cinos - Neuropsychiatry, 2011 - search.proquest.com
The aim of this article is to highlight objective differences between antipsychotic (both first
generation and second generation) long-acting injections (LAIs) and typical and atypical …

Effectiveness of long-acting injectable vs oral antipsychotics in patients with schizophrenia: a meta-analysis of prospective and retrospective cohort studies

T Kishimoto, K Hagi, M Nitta, S Leucht… - Schizophrenia …, 2018 - academic.oup.com
Compared with oral antipsychotics (OAPs), long-acting injectable antipsychotics (LAIs)
should improve medication adherence and reduce relapses in schizophrenia. However …

Historical perspective on antipsychotic long-acting injections

DAW Johnson - The British Journal of Psychiatry, 2009 - cambridge.org
BackgroundClinical experience has shown considerable potential benefits from long-term
continuous medication for chronic or relapsing forms of schizophrenia. These benefits have …

Clinical guideline recommendations for antipsychotic long-acting injections

JM Kane, C Garcia-Ribera - The British Journal of Psychiatry, 2009 - cambridge.org
BackgroundLong-acting injections (LAIs) of antipsychotic drugs were developed over 40
years ago in an attempt to improve the long-term treatment of schizophrenia. AimsTo review …

Long-acting injectable antipsychotics in the treatment of schizophrenia: their role in relapse prevention

O Agid, G Foussias, G Remington - Expert Opinion on …, 2010 - Taylor & Francis
Importance of the field: Antipsychotic medications are the cornerstone of treatment in
schizophrenia, and a large body of data confirms the value of ongoing and continuous …

Long-acting injectable antipsychotics: evidence of effectiveness and use

R Manchanda, P Chue, A Malla… - The Canadian …, 2013 - journals.sagepub.com
Objective To review the evidence for the role of long-acting injectable (LAI) antipsychotics
(APs), especially the second-generation AP (SGA) LAIs, in the treatment of schizophrenia …

[HTML][HTML] Long-acting injectable antipsychotics in first-episode schizophrenia

HG Jeong, MS Lee - Clinical Psychopharmacology and …, 2013 - ncbi.nlm.nih.gov
Antipsychotic medications are important for the successful management of schizophrenia.
Continuous treatment with medication is superior in relapse prevention and non-adherence …

Oral versus long‐acting injectable antipsychotics in the treatment of schizophrenia and special populations at risk for treatment nonadherence: A systematic review

S Zhornitsky, E Stip - Schizophrenia research and treatment, 2012 - Wiley Online Library
Long‐acting injectable antipsychotics (LAIs) should offer better efficacy and tolerability,
compared to oral antipsychotics due to improved adherence and more stable …