Cross-Reactive Surface Epitopes on Chondroitin Sulfate A-Adherent Plasmodium falciparum-Infected Erythrocytes Are Associated with Transcription of var2csa

SR Elliott, MF Duffy, TJ Byrne, JG Beeson… - Infection and …, 2005 - Am Soc Microbiol
Malaria in pregnancy is associated with placental accumulation of Plasmodium falciparum-
infected erythrocytes (IE) that adhere to chondroitin sulfate A (CSA). Adhesion is mediated …

The adhesion of Plasmodium falciparum-infected erythrocytes to chondroitin sulfate A is mediated by P. falciparum erythrocyte membrane protein 1

JC Reeder, AF Cowman, KM Davern… - Proceedings of the …, 1999 - National Acad Sciences
Chondroitin sulfate A (CSA) is an important receptor for the sequestration of Plasmodium
falciparum in the placenta, but the parasite ligand involved in adhesion has not previously …

VAR2CSA is the principal ligand for chondroitin sulfate A in two allogeneic isolates of Plasmodium falciparum

MF Duffy, AG Maier, TJ Byrne, AJ Marty… - Molecular and …, 2006 - Elsevier
Malaria during pregnancy causes serious disease that is associated with sequestration in
the placenta of Plasmodium falciparum infected erythrocytes that adhere to several host …

Characterization of VAR2CSA-deficient Plasmodium falciparum-infected erythrocytes selected for adhesion to the BeWo placental cell line

F Yosaatmadja, KT Andrews, MF Duffy, GV Brown… - Malaria journal, 2008 - Springer
Background Malaria in pregnancy is characterized by accumulation of infected erythrocytes
(IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium …

Recovery of adhesion to chondroitin‐4‐sulphate in Plasmodium falciparum var CSA disruption mutants by antigenically similar PfEMP1 variants

KT Andrews, LA Pirrit, JM Przyborski… - Molecular …, 2003 - Wiley Online Library
Protection against maternal malaria has been associated with the acquisition of a specific
antibody response that prevents adhesion of Plasmodium falciparum‐infected erythrocytes …

Chondroitin sulfate A-adhering Plasmodium falciparum-infected erythrocytes express functionally important antibody epitopes shared by multiple variants

L Barfod, T Dobrilovic, P Magistrado… - The Journal of …, 2010 - journals.aai.org
Acquired protection from Plasmodium falciparum placental malaria, a major cause of
maternal, fetal, and infant morbidity, is mediated by IgG specific for the P. falciparum …

[PDF][PDF] Antibodies among men and children to placental-binding Plasmodium falciparum-infected erythrocytes that express var2csa

JG Beeson, F Ndungu, KEM Persson… - The American journal …, 2007 - academia.edu
During pregnancy, specific variants of Plasmodium falciparum-infected erythrocytes (IEs)
can accumulate in the placenta through adhesion to chondroitin sulfate A (CSA) mediated …

Nonimmune immunoglobulin binding and multiple adhesion characterize Plasmodium falciparum-infected erythrocytes of placental origin

N Rasti, F Namusoke, A Chêne… - Proceedings of the …, 2006 - National Acad Sciences
The harmful effects of pregnancy-associated malaria (PAM) are engendered by the heavy
sequestration of Plasmodium falciparum-parasitized RBCs in the placenta. It is well …

Sequestration of Plasmodium falciparum–infected erythrocytes to chondroitin sulfate A, a receptor for maternal malaria: monoclonal antibodies against the native …

JB Lekana Douki, B Traore, FTM Costa… - Blood, The Journal …, 2002 - ashpublications.org
Plasmodium falciparum parasites express variant adhesion molecules on the surface of
infected erythrocytes (IEs), which act as targets for natural protection. Recently it was shown …

Development of Antibodies against Chondroitin Sulfate A-Adherent Plasmodium falciparum in Pregnant Women

B Maubert, N Fievet, G Tami, M Cot… - Infection and …, 1999 - Am Soc Microbiol
In areas where Plasmodium falciparum is endemic, pregnant women are at increased risk
for malaria, and this risk is greatest during the first pregnancy. The placenta sequesters …