Fecal volatile organic compounds: a novel, cheaper method of diagnosing inflammatory bowel disease?

CSJ Probert, S Reade, I Ahmed - Expert Review of Clinical …, 2014 - Taylor & Francis
The investigation of a novel, cheaper method of diagnosing inflammatory bowel disease
(IBD) is an area of active research. Recently, investigations into the metabolomic profile of …

Investigation of faecal volatile organic metabolites as novel diagnostic biomarkers in inflammatory bowel disease

I Ahmed, R Greenwood, B Costello… - Alimentary …, 2016 - Wiley Online Library
Background The aetiology of inflammatory bowel disease (IBD) remains poorly understood.
Recent evidence suggests an important role of gut microbial dysbiosis in IBD, and this may …

Extending landscape of volatile metabolites as novel diagnostic biomarkers of inflammatory bowel disease–a review

I Ahmed, F Fayyaz, M Nasir, Z Niaz… - Scandinavian Journal …, 2016 - Taylor & Francis
The diagnosis of inflammatory bowel disease (IBD) remains a challenging task despite
significant increase in the understanding of the disease aetiology and pathogenesis. Recent …

An investigation of fecal volatile organic metabolites in irritable bowel syndrome

I Ahmed, R Greenwood, BL Costello, NM Ratcliffe… - PloS one, 2013 - journals.plos.org
Diagnosing irritable bowel syndrome (IBS) can be a challenge; many clinicians resort to
invasive investigations in order to rule out other diseases and reassure their patients …

Volatomics in inflammatory bowel disease and irritable bowel syndrome

K Van Malderen, BY De Winter, G Joris… - …, 2020 - thelancet.com
Volatile organic compounds (VOCs) are produced by the human metabolism, inflammation
and gut microbiota and form the basis of innovative volatomics research. VOCs detected …

A distinct colon-derived breath metabolome is associated with inflammatory bowel disease, but not its complications

F Rieder, S Kurada, D Grove, F Cikach… - Clinical and …, 2016 - journals.lww.com
OBJECTIVES: The accuracy of available noninvasive biomarkers for diagnosis, stratification,
and prediction of inflammatory bowel disease (IBD) courses is limited. We analyzed volatile …

The faecal scent of inflammatory bowel disease: Detection and monitoring based on volatile organic compound analysis

S Bosch, DSJ Wintjens, A Wicaksono… - Digestive and Liver …, 2020 - Elsevier
Background Inflammatory bowel disease (IBD) is diagnosed and monitored using
endoscopic assessment, which is invasive and costly. In this study, potential of faecal …

Potential role of fecal volatile organic compounds as biomarkers of chemically induced intestinal inflammation in mice

S Reade, JM Williams, R Aggio… - The FASEB …, 2019 - Wiley Online Library
Metabolomics studies have the potential to discover biomarkers. Fecal volatile organic
compounds (VOCs) have been found to differ in patients with inflammatory bowel disease …

Volatile organic compounds in exhaled air as novel marker for disease activity in Crohn's disease: a metabolomic approach

AGL Bodelier, A Smolinska, A Baranska… - Inflammatory bowel …, 2015 - academic.oup.com
Background Disappearance of macroscopic mucosal inflammation predicts long-term
outcome in Crohn's disease (CD). It can be assessed by ileocolonoscopy, which is …

Diagnosing Inflammatory bowel disease using noninvasive applications of volatile organic compounds: A systematic review

AS Bannaga, A Farrugia… - Expert Review of …, 2019 - Taylor & Francis
Introduction: Inflammatory bowel disease (IBD) is a common disease with significant
morbidity. Noninvasive diagnostic techniques are lacking in IBD. Currently, fecal calprotectin …