Curcumin and its analogs as potential epigenetic modulators: Prevention of diabetes and its complications

C Tang, Y Liu, S Liu, C Yang, L Chen, F Tang, F Wang… - Pharmacology, 2022 - karger.com
Background: The pathobiology of diabetes and associated complications has been widely
researched in various countries, but effective prevention and treatment methods are still …

Curcumin: a natural product for diabetes and its complications

S Fazel Nabavi, R Thiagarajan… - Current topics in …, 2015 - ingentaconnect.com
Curcumin is the yellow-colored bioactive constituent of the perennial plant, Curcuma longa
L., which possesses a wide range of physiological and pharmacological properties such as …

[HTML][HTML] Curcumin and type 2 diabetes mellitus: prevention and treatment

F Pivari, A Mingione, C Brasacchio, L Soldati - Nutrients, 2019 - mdpi.com
Type 2 diabetes mellitus (T2DM) is an ensemble of metabolic diseases that has reached
pandemic dimensions all over the world. The multifactorial nature of the pathology makes …

[HTML][HTML] “Curcumin, the king of spices”: epigenetic regulatory mechanisms in the prevention of cancer, neurological, and inflammatory diseases

SSS Boyanapalli, ANT Kong - Current pharmacology reports, 2015 - Springer
Curcumin (diferuloylmethane), a polyphenolic compound, is a component of Curcuma
longa, commonly known as turmeric. It is a well-known anti-inflammatory, anti-oxidative, and …

Antidiabetic activity of curcumin: Insight Into its mechanisms of action

M Wojcik, M Krawczyk, LA Wozniak - Nutritional and therapeutic …, 2018 - Elsevier
Oxidative stress, defined as the imbalance between formation of reactive oxygen and
nitrogen species (ROS/RNS) and their elimination, has been implicated in the development …

Curcumin and its allied analogues: epigenetic and health perspectives-a review

M Imran, M Nadeem, MA Khan, S Ahmed, A Imran… - 2017 - dro.deakin.edu.au
Curcumin (diferuoyl methane) is a yellow active ingredient present in turmeric. It is a
homodimer of feruloylmethane that comprises a hydroxyl and methoxy group (heptadiene …

An update on molecular mechanisms of curcumin effect on diabetes

W Lu, F Khatibi Shahidi, K Khorsandi… - Journal of food …, 2022 - Wiley Online Library
Owing to its prevalent nature, diabetes mellitus has become one of the most serious
endocrine illnesses affecting a patient's quality of life due to the manifestation of side effects …

Antidiabetic properties of curcumin: insights on new mechanisms

E Mohammadi, B Behnam, R Mohammadinejad… - Studies on Biomarkers …, 2021 - Springer
Plant extracts have been used to treat a wide range of human diseases. Curcumin, a
bioactive polyphenol derived from Curcuma longa L., exhibits therapeutic effects against …

Therapeutic potential of curcumin in diabetic complications

N Parsamanesh, M Moossavi, A Bahrami… - Pharmacological …, 2018 - Elsevier
Diabetes mellitus is an extremely prevalent endocrine disease and a major global public
health concern. Diabetic complications, such as retinopathy, nephropathy, neuropathy and …

[HTML][HTML] How curcumin targets inflammatory mediators in diabetes: therapeutic insights and possible solutions

Y Hussain, H Khan, G Alotaibi, F Khan, W Alam… - Molecules, 2022 - mdpi.com
Diabetes mellitus is a multifactorial chronic metabolic disorder, characterized by altered
metabolism of macro-nutrients, such as fats, proteins, and carbohydrates. Diabetic …