Controlled release of a therapeutic peptide in sprayable surgical sealant for prevention of postoperative abdominal adhesions
Formation of asymmetric, rigid scar tissue known as surgical adhesions is caused by
traumatic disruption of mesothelial-lined surfaces in surgery. A widely adopted prophylactic …
traumatic disruption of mesothelial-lined surfaces in surgery. A widely adopted prophylactic …
Rapid and coagulation-independent haemostatic sealing by a paste inspired by barnacle glue
Tissue adhesives do not normally perform well on tissues that are covered with blood or
other bodily fluids. Here we report the design, adhesion mechanism and performance of a …
other bodily fluids. Here we report the design, adhesion mechanism and performance of a …
Novel wound sealants: Biomaterials and applications
HT Peng, PN Shek - Expert review of medical devices, 2010 - Taylor & Francis
Wound sealants provide an excellent alternative for closing surgical and non-surgical
wounds, as well as stopping external bleeding for prehospital trauma injuries. Numerous …
wounds, as well as stopping external bleeding for prehospital trauma injuries. Numerous …
An endoscopically compatible fast-gelation powder forms Janus-adhesive hydrogel barrier to prevent postoperative adhesions
Postoperative adhesions occur widely in various tissues, bringing the risk of secondary
surgery and increased medical burden. Hydrogel barriers with Janus-adhesive ability can …
surgery and increased medical burden. Hydrogel barriers with Janus-adhesive ability can …
Engineered hemostatic biomaterials for sealing wounds
Hemostatic biomaterials show great promise in wound control for the treatment of
uncontrolled bleeding associated with damaged tissues, traumatic wounds, and surgical …
uncontrolled bleeding associated with damaged tissues, traumatic wounds, and surgical …
[HTML][HTML] Liquid-infused microstructured bioadhesives halt non-compressible hemorrhage
Non-compressible hemorrhage is an unmet clinical challenge that accounts for high
mortality in trauma. Rapid pressurized blood flows under hemorrhage impair the function …
mortality in trauma. Rapid pressurized blood flows under hemorrhage impair the function …
A double crosslinking adhesion mechanism for developing tough hydrogel adhesives
Tough hydrogel adhesives that consist of a robust gel network and can strongly adhere to
wet tissues have shown great promise as the next generation of bioadhesives. While a …
wet tissues have shown great promise as the next generation of bioadhesives. While a …
An injectable and instant self-healing medical adhesive for wound sealing
Designing versatile functional medical adhesives with injectability, self-healing, and strong
adhesion is of great significance to achieve desirable therapeutic effects for promoting …
adhesion is of great significance to achieve desirable therapeutic effects for promoting …
Sequential‐Crosslinking Fibrin Glue for Rapid and Reinforced Hemostasis
L Yu, Z Liu, Z Tong, Y Ding, Z Qian, W Wang… - Advanced …, 2024 - Wiley Online Library
Achieving hemostasis effectively is essential for surgical success and excellent patient
outcomes. However, it is challenging to develop hemostatic adhesives that are fast‐acting …
outcomes. However, it is challenging to develop hemostatic adhesives that are fast‐acting …
A biodegradable and biocompatible gecko-inspired tissue adhesive
A Mahdavi, L Ferreira, C Sundback… - Proceedings of the …, 2008 - National Acad Sciences
There is a significant medical need for tough biodegradable polymer adhesives that can
adapt to or recover from various mechanical deformations while remaining strongly attached …
adapt to or recover from various mechanical deformations while remaining strongly attached …