Background An isoleucine> methionine mutation at position 148 in the PNPLA3 gene (p.
I148M, rs738409) has recently been identified as a susceptibility factor for liver damage in …

Background and aim: The PNPLA3 rs738409 C> G polymorphism has been found to be
strongly associated with non‐alcoholic fatty liver disease and with alcoholic liver disease …

Background & Aims Subtle inter-patient genetic variation and environmental factors combine
to determine disease progression in non-alcoholic fatty liver disease (NAFLD). Carriage of …

BACKGROUND & AIMS: Several studies have reported an association between the genetic
variant rs738409 (G) in the PNPLA3 gene and the risk of cirrhosis in various liver diseases …

Background PNPLA3 rs738409 polymorphism is associated with fatty liver disease,
alcoholic or non-alcoholic (NAFLD) and hepatocellular carcinoma (HCC). TM6SF2 …

The incidence of hepatocellular carcinoma (HCC) is increasing in Western countries.
Although several clinical factors have been identified, many individuals never develop HCC …

Abstract Background & Aims Environmental and genetic factors contribute to alcoholic
cirrhosis onset. In particular, age at exposure to liver stressors has been shown to be …

Background & Aims Aim of this study was to evaluate whether the PNPLA3 I148M
polymorphism, previously associated with hepatocellular carcinoma (HCC) risk, influences …

Aim The PNPLA3 rs738409 C> G polymorphism (encoding for I148M) has recently been
identified as a susceptibility factor for steatosis‐mediated liver damage. We evaluated the …

Purpose: The correlation between patatin-like phospholipase domain-containing protein 3
(PNPLA3) rs738409 polymorphism and hepatocellular carcinoma was investigated by …