The epigenetic landscape of differentiated thyroid cancer
Differentiated thyroid carcinoma of follicular cell-derivation is the most common endocrine
neoplasm with a rapidly increasing incidence. The majority represent papillary carcinomas; …
neoplasm with a rapidly increasing incidence. The majority represent papillary carcinomas; …
Perspective: lessons learned from molecular genetic studies of thyroid cancer—insights into pathogenesis and tumor-specific therapeutic targets
JA Fagin - Endocrinology, 2002 - academic.oup.com
Thyroid cancer derived from follicular cells is the most common endocrine malignancy. The
past decade has seen progress in our understanding of the pathogenesis of the various …
past decade has seen progress in our understanding of the pathogenesis of the various …
Molecular and genetic markers of follicular-cell thyroid cancer: etiology and diagnostic and therapeutic opportunities
N Goyal, D Setabutr, J Abdulghani… - Impact of Genetic Targets …, 2013 - Springer
Thyroid cancer has an increasing incidence in the US population and worldwide, with 95%
of the cancers being of follicular cell origin—papillary, follicular, or anaplastic thyroid …
of the cancers being of follicular cell origin—papillary, follicular, or anaplastic thyroid …
[HTML][HTML] Molecular genetics of follicular-derived thyroid cancer
E Macerola, AM Poma, P Vignali, A Basolo, C Ugolini… - Cancers, 2021 - mdpi.com
Simple Summary Thyroid tumors that derive from follicular cells are not a homogeneous
entity, showing variable morphological appearance and different degrees of differentiation …
entity, showing variable morphological appearance and different degrees of differentiation …
Epigenetic dysregulation in thyroid neoplasia
Gain-of-function mutations in oncogenes have aided our understanding of the molecular
mechanisms of thyroid carcinogenesis. Mutations or deletions cause inactivation of tumor …
mechanisms of thyroid carcinogenesis. Mutations or deletions cause inactivation of tumor …
Well differentiated follicular thyroid neoplasia: impact of molecular and technological advances on detection, monitoring and treatment
AG Gianoukakis, SM Giannelli, WA Salameh… - Molecular and cellular …, 2011 - Elsevier
Our understanding of the molecular mechanisms responsible for follicular thyroid cell
oncogenesis has been advanced significantly in recent years. Specific genetic alterations …
oncogenesis has been advanced significantly in recent years. Specific genetic alterations …
Genetic considerations in thyroid cancer
KN Patel, B Singh - Cancer control, 2006 - journals.sagepub.com
Background Recent molecular studies have described a number of abnormalities
associated with the progression and dedifferentiation of thyroid carcinoma. These distinct …
associated with the progression and dedifferentiation of thyroid carcinoma. These distinct …
Genomic hallmarks of thyroid neoplasia
TJ Giordano - Annual Review of Pathology: Mechanisms of …, 2018 - annualreviews.org
The genomic landscape of thyroid cancers that are derived from follicular cells has been
substantially elucidated through the coordinated application of high-throughput genomic …
substantially elucidated through the coordinated application of high-throughput genomic …
[HTML][HTML] Thyroid carcinoma: phenotypic features, underlying biology and potential relevance for targeting therapy
J Hu, IJ Yuan, S Mirshahidi, A Simental, SC Lee… - International journal of …, 2021 - mdpi.com
Thyroid carcinoma consists a group of phenotypically heterogeneous cancers. Recent
advances in biological technologies have been advancing the delineation of genetic …
advances in biological technologies have been advancing the delineation of genetic …
Pathogenesis of cancers derived from thyroid follicular cells
The genomic simplicity of differentiated cancers derived from thyroid follicular cells offers
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
unique insights into how oncogenic drivers impact tumour phenotype. Essentially, the main …
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