Risk factors for the development of specific noncardiovascular adverse effects associated with amiodarone
JE Tisdale, SL Follin, A Ordelova… - The Journal of Clinical …, 1995 - Wiley Online Library
Noncardiovascular adverse effects associated with amiodarone result in substantial
morbidity. Adverse effects involving the skin, liver, thyroid, and lungs have been reported in …
morbidity. Adverse effects involving the skin, liver, thyroid, and lungs have been reported in …
Antiarrhythmic agents and the risk of malignant neoplasm of liver and intrahepatic bile ducts
Background The objective of this study was to determine the association between the use of
antiarrhythmic agents and the risk of malignant neoplasm of liver and intrahepatic bile ducts …
antiarrhythmic agents and the risk of malignant neoplasm of liver and intrahepatic bile ducts …
[HTML][HTML] Fatal acute liver failure with intravenous amiodarone: a case report and literature review
Amiodarone is a drug which frequently causes elevated transaminases. However, acute
liver failure has been rarely reported. Here, we present a case of fatal acute liver failure …
liver failure has been rarely reported. Here, we present a case of fatal acute liver failure …
Pleiotropic actions of amiodarone: still puzzling after half a century
Amiodarone was developed in the early 1960s based on extracts from the Khella plant and
was initially used as a coronary dilator for the treatment of angina pectoris (Singh 2008). In …
was initially used as a coronary dilator for the treatment of angina pectoris (Singh 2008). In …
[HTML][HTML] Acute hepatitis after amiodarone infusion
P Fonseca, A Dias, H Gonçalves… - World Journal of …, 2015 - ncbi.nlm.nih.gov
Acute hepatitis is a very rare, but potentially fatal, adverse effect of intravenous amiodarone.
We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy …
We present a case of an 88-year-old man with history of ischemic dilated cardiomyopathy …
Establishment of a mouse model for amiodarone‐induced liver injury and analyses of its hepatotoxic mechanism
S Takai, S Oda, K Tsuneyama, T Fukami… - Journal of Applied …, 2016 - Wiley Online Library
Drug‐induced liver injury (DILI) is the most frequent cause of post‐marketing warnings and
withdrawals. Amiodarone (AMD), an antiarrhythmic, presents a risk of liver injury in humans …
withdrawals. Amiodarone (AMD), an antiarrhythmic, presents a risk of liver injury in humans …
Population-level incidence and risk factors for pulmonary toxicity associated with amiodarone
CA Jackevicius, A Tom, V Essebag… - The American journal of …, 2011 - Elsevier
Estimates from clinical trials and small observational studies of the incidence of pulmonary
toxicity (PT) associated with amiodarone range from 1% to 10%. We report a unique study of …
toxicity (PT) associated with amiodarone range from 1% to 10%. We report a unique study of …
Amiodarone-induced liver injury and cirrhosis
J Buggey, M Kappus, AS Lagoo… - ACG case reports …, 2015 - journals.lww.com
We present a case report of an 80-year-old woman with volume overload thought initially to
be secondary to heart failure, but determined to be amiodarone-induced acute and chronic …
be secondary to heart failure, but determined to be amiodarone-induced acute and chronic …
Amiodarone and the risk of cancer: a nationwide population‐based study
BACKGROUND: In postmarketing surveillance, the US Food and Drug Administration has
reported the development of lung masses, thyroid cancer, and skin cancer after amiodarone …
reported the development of lung masses, thyroid cancer, and skin cancer after amiodarone …
Adverse effects of low dose amiodarone: a meta-analysis
VR Vorperian, TC Havighurst, S Miller… - Journal of the American …, 1997 - jacc.org
Objectives. We sought to assess the odds of experiencing adverse effects with low dose
amiodarone therapy compared with placebo. Background. An estimate of the likelihood of …
amiodarone therapy compared with placebo. Background. An estimate of the likelihood of …