The reciprocal translocation t (7; 12)(q36; p13) gives rise to acute myeloid leukemia (AML) in
infants and very young children. A fusion transcript MNX1:: ETV6 is sometimes detected and …

Abstract The t (7; 12)(q36; p13)(MNX1/ETV6) is not included in the WHO classification but
has been described in up to 30% of acute myeloid leukemia (AML) in children< 2 years and …

Cytogenetic aberrations are often involved in acute myeloid leukemia (AML) and can serve
as diagnostic markers, prognosis predictors and impact the choice of therapy. A …

Patients with infant acute myeloid leukemia (AML) who carry at (7; 12)(q36; p13)
translocation have been reported to have a poor clinical outcome. MNX1–ETV6 fusion …

Acute myeloid leukemia (AML) with the t (7; 12)(q36; p13) translocation occurs only in very
young children and has a poor clinical outcome. The expected oncofusion between …

Acute myeloid leukaemia (AML), typically a disease of elderly adults, affects 8 children per
million each year, with the highest paediatric incidence in infants aged 0–2 of 18 per million …

A complex three-way t (8; 18; 16)(p11; q21; p13) was detected in a 15-month-old patient with
acute myeloid leukemia (AML). The patient had typical clinical manifestation and bone …

Certain subtypes of acute myeloid leukemia (AML) in children have inferior outcome, such
as AML with translocation t (7; 12)(q36; p13) leading to an MNX1:: ETV6 fusion along with …

Using both conventional and molecular cytogenetic methods, we found five new cases of t
(10; 11)(p12; q23). This translocation represented 28% of all cases of childhood AML treated …

Introduction: Non-random cytogenetic aberrations are often involved in the development of
AML in children and several aberrations can serve as diagnostic markers, prognosis …