In 16 male patients with heart failure (NYHA II-III), the influence of a single dose of 25 mg
captopril on the carotid sinus baroreceptor reflex was examined. Blood presure fell …

Captopril lowers blood pressure without increasing heart rate and plasma norepinephrine,
which suggests that this drug may potentiate arterial baroreflexes. In eight subjects with …

1. The reflex effects of intravenous phenylephrine, sodium nitroprusside or acute
haemorrhage in rabbits were examined as indices of baroreceptors reflex function. 2. The …

The deranged autonomic control of heart rate was studied in 34 patients with heart failure
(New York Heart Association [NYHA] functional class II to III) by examining the carotid sinus …

Absent reflex tachycardia with captopril therapy suggests blunting of circulatory reflexes,
perhaps contributing to antihypertensive efficacy, and angiotensin converting enzyme …

Decreased sensitivity of cardiopulmonary and arterial baroreceptors has been hypothe
sized to sustain sympathetic activation in patients with heart failure. In the present inves …

We have previously demonstrated a decrease in baroreceptor discharge sensitivity in dogs
with experimental heart failure. In the present study, we determined the sensitivity of the …

1 The effect of captopril on autonomic reflex functions has been investigated in fifteen
patients with essential hypertension by examining their responses to tests of baroreceptor …

Single-unit carotid sinus baroreceptor activity was recorded in normal and heart-failure
(pacing-induced) dogs. The sensitivity of these units was compared between the two groups …

The hemodynamic effects of a single dose of 5 mg of ramipril, a new angiotensin converting
enzyme inhibitor, were investigated in 10 patients with chronic congestive heart failure …