Extracellular vesicles and oncogenic signaling

A Schubert, M Boutros - Molecular oncology, 2021 - Wiley Online Library
In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic
markers for cancer therapy. While the field of EV research is rapidly developing and their …

Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer

V Torrano, F Royo, H Peinado, A Loizaga-Iriarte… - Current opinion in …, 2016 - Elsevier
Highlights•Extracellular vesicles (EVs) are secreted virtually by all cell types and vary in
cargo and composition.•Cancer cells exhibit altered EV composition.•The presence of EVs in …

Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications

R Rahbarghazi, N Jabbari, NA Sani, R Asghari… - Cell Communication and …, 2019 - Springer
Background Studies have recently revealed that almost every type of cells including tumor
cells abundantly release small vesicles known as extracellular vesicles (EVs) into the …

[HTML][HTML] Implications and pitfalls for cancer diagnostics exploiting extracellular vesicles

A Špilak, A Brachner, U Kegler, W Neuhaus… - Advanced drug delivery …, 2021 - Elsevier
Early detection of cancer in order to facilitate timely therapeutic interventions is an unsolved
problem in today's clinical diagnostics. Tumors are detected so far mostly after pathological …

Tumor-derived extracellular vesicles: molecular parcels that enable regulation of the immune response in cancer

C Sheehan, C D'Souza-Schorey - Journal of cell science, 2019 - journals.biologists.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound vesicles
released by cells that contain bioactive cargoes including proteins, lipids and nucleic acids …

Signaling by extracellular vesicles advances cancer hallmarks

M Kanada, MH Bachmann, CH Contag - Trends in cancer, 2016 - cell.com
Mammalian cells secrete various extracellular vesicles (EVs; exosomes, microvesicles, and
apoptotic bodies) that differ in biogenesis, composition, and function. Each vesicle type can …

Extracellular vesicle transfer of cancer pathogenic components

Y Fujita, Y Yoshioka, T Ochiya - Cancer science, 2016 - Wiley Online Library
Extracellular vesicles (EV), known as exosomes and microvesicles, serve as versatile
intercellular communication vehicles. Increasing evidence has shown that cancer cell …

Proteomic analysis of extracellular vesicles for cancer diagnostics

AYT Wu, K Ueda, CPK Lai - Proteomics, 2019 - Wiley Online Library
Extracellular vesicles (EVs) including exosomes and microvesicles are lipid bilayer‐
encapsulated nanoparticles released by cells, ranging from 40 nm to several microns in …

Imaging extracellular vesicles: current and emerging methods

STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …

Cancer therapy based on extracellular vesicles as drug delivery vehicles

L Cabeza, G Perazzoli, M Peña, A Cepero… - Journal of controlled …, 2020 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer vesicles of nanometric size secreted by cells to
communicate with other cells, either nearby or remotely. Their physicochemical properties …