Extracellular vesicles and oncogenic signaling
A Schubert, M Boutros - Molecular oncology, 2021 - Wiley Online Library
In recent years, extracellular vesicles (EVs) emerged as potential diagnostic and prognostic
markers for cancer therapy. While the field of EV research is rapidly developing and their …
markers for cancer therapy. While the field of EV research is rapidly developing and their …
Vesicle-MaNiA: extracellular vesicles in liquid biopsy and cancer
Highlights•Extracellular vesicles (EVs) are secreted virtually by all cell types and vary in
cargo and composition.•Cancer cells exhibit altered EV composition.•The presence of EVs in …
cargo and composition.•Cancer cells exhibit altered EV composition.•The presence of EVs in …
Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications
R Rahbarghazi, N Jabbari, NA Sani, R Asghari… - Cell Communication and …, 2019 - Springer
Background Studies have recently revealed that almost every type of cells including tumor
cells abundantly release small vesicles known as extracellular vesicles (EVs) into the …
cells abundantly release small vesicles known as extracellular vesicles (EVs) into the …
[HTML][HTML] Implications and pitfalls for cancer diagnostics exploiting extracellular vesicles
A Špilak, A Brachner, U Kegler, W Neuhaus… - Advanced drug delivery …, 2021 - Elsevier
Early detection of cancer in order to facilitate timely therapeutic interventions is an unsolved
problem in today's clinical diagnostics. Tumors are detected so far mostly after pathological …
problem in today's clinical diagnostics. Tumors are detected so far mostly after pathological …
Tumor-derived extracellular vesicles: molecular parcels that enable regulation of the immune response in cancer
C Sheehan, C D'Souza-Schorey - Journal of cell science, 2019 - journals.biologists.com
Extracellular vesicles (EVs) are a heterogeneous collection of membrane-bound vesicles
released by cells that contain bioactive cargoes including proteins, lipids and nucleic acids …
released by cells that contain bioactive cargoes including proteins, lipids and nucleic acids …
Signaling by extracellular vesicles advances cancer hallmarks
Mammalian cells secrete various extracellular vesicles (EVs; exosomes, microvesicles, and
apoptotic bodies) that differ in biogenesis, composition, and function. Each vesicle type can …
apoptotic bodies) that differ in biogenesis, composition, and function. Each vesicle type can …
Extracellular vesicle transfer of cancer pathogenic components
Y Fujita, Y Yoshioka, T Ochiya - Cancer science, 2016 - Wiley Online Library
Extracellular vesicles (EV), known as exosomes and microvesicles, serve as versatile
intercellular communication vehicles. Increasing evidence has shown that cancer cell …
intercellular communication vehicles. Increasing evidence has shown that cancer cell …
Proteomic analysis of extracellular vesicles for cancer diagnostics
Extracellular vesicles (EVs) including exosomes and microvesicles are lipid bilayer‐
encapsulated nanoparticles released by cells, ranging from 40 nm to several microns in …
encapsulated nanoparticles released by cells, ranging from 40 nm to several microns in …
Imaging extracellular vesicles: current and emerging methods
STY Chuo, JCY Chien, CPK Lai - Journal of biomedical science, 2018 - Springer
Extracellular vesicles (EVs) are lipid bilayer-enclosed nanoparticles released by cells. They
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
range from 30 nm to several micrometers in diameter, and ferry biological cargos such as …
Cancer therapy based on extracellular vesicles as drug delivery vehicles
L Cabeza, G Perazzoli, M Peña, A Cepero… - Journal of controlled …, 2020 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer vesicles of nanometric size secreted by cells to
communicate with other cells, either nearby or remotely. Their physicochemical properties …
communicate with other cells, either nearby or remotely. Their physicochemical properties …