[HTML][HTML] Mechanistic insight and clinical implications of ischemia/reperfusion injury post liver transplantation

J Liu, K Man - Cellular and molecular gastroenterology and …, 2023 - Elsevier
Ischemia/reperfusion injury is an inevitable process during liver transplantation and can lead
to a high incidence of early allograft dysfunction and graft failure. The mechanism of hepatic …

New insights in mechanisms and therapeutics for short-and long-term impacts of hepatic ischemia reperfusion injury post liver transplantation

H Liu, K Man - International journal of molecular sciences, 2021 - mdpi.com
Liver transplantation has been identified as the most effective treatment for patients with end-
stage liver diseases. However, hepatic ischemia reperfusion injury (IRI) is associated with …

Hepatic ischemia reperfusion injury: contemporary perspectives on pathogenic mechanisms and basis for hepatoprotection—the good, bad and deadly

NC Teoh - Journal of gastroenterology and hepatology, 2011 - Wiley Online Library
Hepatic ischemia reperfusion (IR) injury is an important clinical problem complicating liver
surgery and transplantation. The pathogenesis underlying reperfusion injury after warm …

[HTML][HTML] Hepatic ischemia-reperfusion injury with respect to oxidative stress and inflammatory response: a narrative review

EK Choi, DG Lim - Journal of Yeungnam Medical Science, 2022 - synapse.koreamed.org
Hepatic ischemia-reperfusion injury is a major complication of liver transplantation, trauma,
and shock. This pathological condition can lead to graft dysfunction and rejection in the field …

Hepatic ischemia/reperfusion injury—a fresh look

C Fondevila, RW Busuttil… - … and molecular pathology, 2003 - Elsevier
Ischemia/reperfusion (I/R) injury is a multifactorial process that affects graft function after liver
transplantation. An understanding of the mechanisms involved in I/R injury is essential for …

[HTML][HTML] Molecular mechanisms of liver ischemia reperfusion injury: insights from transgenic knockout models

G Datta, BJ Fuller, BR Davidson - World journal of …, 2013 - ncbi.nlm.nih.gov
Ischemia reperfusion injury is a major obstacle in liver resection and liver transplantation
surgery. Understanding the mechanisms of liver ischemia reperfusion injury (IRI) and …

Molecular pathways in protecting the liver from ischaemia/reperfusion injury: a 2015 update

J Gracia-Sancho, A Casillas-Ramirez… - Clinical Science, 2015 - portlandpress.com
Ischaemia/reperfusion injury is an important cause of liver damage during surgical
procedures such as hepatic resection and liver transplantation, and represents the main …

Ischaemia–reperfusion injury in liver transplantation—from bench to bedside

Y Zhai, H Petrowsky, JC Hong, RW Busuttil… - Nature reviews …, 2013 - nature.com
Ischaemia–reperfusion injury (IRI) in the liver, a major complication of haemorrhagic shock,
resection and transplantation, is a dynamic process that involves the two interrelated phases …

Abrogation of graft ischemia‐reperfusion injury in ischemia‐free liver transplantation

Z Guo, J Xu, S Huang, M Yin, Q Zhao… - Clinical and …, 2022 - Wiley Online Library
Background Ischemia‐reperfusion injury (IRI) is considered an inherent component of organ
transplantation that compromises transplant outcomes and organ availability. The ischemia …

Ischemia/Reperfusion injury in liver surgery and transplantation: pathophysiology

K Weigand, S Brost, N Steinebrunner, M Büchler… - HPB …, 2012 - Wiley Online Library
Liver ischemia/reperfusion (IR) injury is caused by a heavily toothed network of interactions
of cells of the immune system, cytokine production, and reduced microcirculatory blood flow …