Therapeutic management of locally advanced, recurrent and metastatic head and neck
squamous cell carcinoma (HNSCC) is often limited by a rather unfavorable efficacy and …

Targeting specific biological pathways in tumor development has been heralded as a
promising approach to the treatment of cancer. Familiar to most investigators are the studies …

The treatment of squamous cell carcinoma of the head and neck (SCCHN) has recently
witnessed the introduction of molecularly targeted agents based on disease biology, target …

Recently, new targets have been identified in head and neck squamous cell carcinomas
(HNSCC) as playing key roles in tumour proliferation and metastases. The first target that …

Current development of molecular targeted therapies in oncology is particularly active. The
aim of this study is to review recent advances in the field of molecular targeted therapies for …

Despite recent advances in radiotherapy and chemotherapy, survival rates for squamous
cell carcinoma of the head and neck (SCCHN) have remained poor. The focus of SCCHN …

Despite significant advances in the use of surgery, chemotherapy and radiotherapy to treat
squamous cell carcinoma of the head and neck (SCCHN), prognosis has improved little over …

Current development of molecular targeted therapies in oncology is particularly active. This
paper is a review of the recent advances in the field of molecular targeted therapies for head …

In this review, key aspects of epidermal growth factor receptor (EGFR) biology and the fruitful
translation of these fundamental findings into recent treatment advances in head and neck …

Over the past decade, the important role of different growth factors and their receptors and
signal transduction pathways in the genesis and progression of tumors has been well …