Apo E4 and lipoprotein-associated phospholipase A2 synergistically increase cardiovascular risk
Z Gungor, E Anuurad, B Enkhmaa, W Zhang, K Kim… - Atherosclerosis, 2012 - Elsevier
OBJECTIVE: Apolipoprotein E (apoE) has been implicated as conveying increased risk for
coronary artery disease (CAD). Previous studies suggest a role of apoE as a modulator of …
coronary artery disease (CAD). Previous studies suggest a role of apoE as a modulator of …
Associations of apolipoprotein E exon 4 and lipoprotein lipase S447X polymorphisms with acute ischemic stroke and myocardial infarction
L Baum, H Keung Ng, KS Wong… - Clinical Chemistry and …, 2006 - degruyter.com
Abstract Background: Because apolipoprotein E (apoE) and lipopoprotein lipase (LPL)
polymorphisms interact with each other and with other factors to affect lipid metabolism, we …
polymorphisms interact with each other and with other factors to affect lipid metabolism, we …
Apolipoprotein E is associated with blood lipids and inflammation in Taiwanese older adults
Polymorphisms of the apolipoprotein E gene (ApoE) have been associated with health and
longevity. Numerous studies have linked ApoE to health outcomes including cardiovascular …
longevity. Numerous studies have linked ApoE to health outcomes including cardiovascular …
APOE Genotypes Modulate Inflammation Independently of Their Effect on Lipid Metabolism
M Civeira-Marín, A Cenarro, V Marco-Benedí… - International Journal of …, 2022 - mdpi.com
The association between APOE genotypes and cardiovascular disease (CVD) is partially
mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels and …
mediated by LDL-cholesterol concentration but persists after adjusting for lipid levels and …
[HTML][HTML] Effects of apoE genotype on macrophage inflammation and heme oxygenase-1 expression
L Jofre-Monseny, A Loboda, AE Wagner… - Biochemical and …, 2007 - Elsevier
In order to gain a more comprehensive understanding of the aetiology of apolipoprotein E4
genotype-cardiovascular disease (CVD) associations, the impact of the apoE genotype on …
genotype-cardiovascular disease (CVD) associations, the impact of the apoE genotype on …
Interactive effects of C-reactive protein levels on the association between APOE variants and triglyceride levels in a Taiwanese population
S Wu, LA Hsu, MS Teng, JF Lin, HH Chou… - Lipids in health and …, 2016 - Springer
Abstract Background Apolipoprotein E (APOE) plays a major role in lipid metabolism and
inflammation. However, the association between APOE gene polymorphisms and serum …
inflammation. However, the association between APOE gene polymorphisms and serum …
Apolipoprotein E polymorphism influence on lipids, apolipoproteins and Lp (a) in a Spanish population underexpressing apo E4
M Muros, C Rodríguez-Ferrer - Atherosclerosis, 1996 - Elsevier
The apolipoprotein E (apo E) polymorphism in a Spanish working population of Tenerife
(Canary Islands, Spain) was analyzed. The distribution of apo E alleles (ε3, 0.850; ε2, 0.075; …
(Canary Islands, Spain) was analyzed. The distribution of apo E alleles (ε3, 0.850; ε2, 0.075; …
Investigating effects of plasma apolipoprotein E on ischemic heart disease using Mendelian randomization study
MY Li, MK Kwok, CM Schooling - Nutrients, 2021 - mdpi.com
Background: Observationally plasma apolipoprotein E (apoE) is positively associated with
ischemic heart disease (IHD). A Mendelian randomization (MR) study suggesting apoE is …
ischemic heart disease (IHD). A Mendelian randomization (MR) study suggesting apoE is …
Apolipoprotein E suppresses the type I inflammatory response in vivo
K Ali, M Middleton, E Puré, DJ Rader - Circulation research, 2005 - Am Heart Assoc
Apolipoprotein E (apoE) is synthesized in the liver and in macrophages, and it has
antiatherogenic properties that are mediated, at least in part, through the regulation of …
antiatherogenic properties that are mediated, at least in part, through the regulation of …
Relationship of the ApoE polymorphism to plasma lipid traits among South Asians, Chinese, and Europeans living in Canada
BACKGROUND: The prevalence of cardiovascular risk factors and atherosclerosis vary
between ethnic groups. We examined the apolipoprotein E (ApoE) polymorphism, its …
between ethnic groups. We examined the apolipoprotein E (ApoE) polymorphism, its …