The quasi-static mechanical behaviour of the aortic valve (AV) is highly non-linear and
anisotropic in nature and reflects the complex collagen fibre kinematics in response to …

Mechanical stresses on aortic valve leaflets are well-known mediators for initiating
processes leading to calcific aortic valve disease. Given that non-coronary leaflets calcify …

Failure of synthetic heart valves is usually caused by tearing and calcification of the leaflets.
Leaflet fiber-reinforcement increases the durability of these values by unloading the delicate …

Normal physiological mechanical forces cause constant tissue renewal in aortic valve
leaflets (AVL) while altered mechanical forces incite changes in their structural and …

Mechanical heart valve replacement is the preferred alternative in younger patients with
severe symptomatic aortic valve disease. However, thrombus and pannus formations are …

Soft tissues, such as tendons, skin, arteries, or lung, are constantly subject to mechanical
stresses in vivo. None more so than the aortic heart valve that experiences an array of forces …

Aortic valve diseases are among the most common cardiovascular defects. Since a non-
functioning valve results in disturbed blood flow conditions, the diagnosis of such defects is …

Calcific aortic valve disease (CAVD) is a progressive pathology characterized by
calcification mainly within the cusps of the aortic valve (AV). As CAVD advances, the blood …

The leaflets of the aortic valve move extremely rapidly during opening and closing. To
analyse this movement, radiopaque markers were placed on the aortic valves of four dogs …

The stress analysis of the porcine aortic valve leaflets in diastole at 80 mm Hg pressure in-
vitro is presented. Incorporation of local geometrical asymmetry, material inhomogeneity …