Two-photon voltage imaging has long been heralded as a transformative approach capable
of answering many long-standing questions in modern neuroscience. However, exploiting …

Monitoring spiking activity across large neuronal populations at behaviorally relevant
timescales is critical for understanding neural circuit function. Unlike calcium imaging …

Monitoring voltage dynamics in defined neurons deep in the brain is critical for unraveling
the function of neuronal circuits but is challenging due to the limited performance of existing …

Genetically encoded voltage indicators are emerging tools for monitoring voltage dynamics
with cell-type specificity. However, current indicators enable a narrow range of applications …

Voltage-sensitive fluorescent proteins (VSFPs) are a family of genetically-encoded voltage
indicators (GEVIs) reporting membrane voltage fluctuation from genetically-targeted cells in …

Voltage imaging of many neurons simultaneously at single-cell resolution is hampered by
the difficulty of detecting small voltage signals from overlapping neuronal processes in …

Imaging of transmembrane voltage deep in brain tissue with cellular resolution has the
potential to reveal information processing by neuronal circuits in living animals with minimal …

The ability to probe the membrane potential of multiple genetically defined neurons
simultaneously would have a profound impact on neuroscience research. Genetically …

Genetically encoded voltage indicators (GEVIs) enable optical recording of electrical signals
in the brain, providing subthreshold sensitivity and temporal resolution not possible with …

Optical methods that rely on fluorescence for mapping changes in neuronal membrane
potential in the brains of awake animals provide a powerful way to interrogate the activity of …