IRT1, an Arabidopsis transporter essential for iron uptake from the soil and for plant growth

G Vert, N Grotz, F Dédaldéchamp, F Gaymard… - The plant …, 2002 - academic.oup.com
Plants are the principal source of iron in most diets, yet iron availability often limits plant
growth. In response to iron deficiency, Arabidopsis roots induce the expression of the …

Expression of the IRT1 metal transporter is controlled by metals at the levels of transcript and protein accumulation

EL Connolly, JP Fett, ML Guerinot - The Plant Cell, 2002 - academic.oup.com
Iron, an essential nutrient, is not readily available to plants because of its low solubility. In
addition, iron is toxic in excess, catalyzing the formation of hydroxyl radicals that can …

Arabidopsis IRT2 cooperates with the high-affinity iron uptake system to maintain iron homeostasis in root epidermal cells

G Vert, M Barberon, E Zelazny, M Séguéla, JF Briat… - Planta, 2009 - Springer
Iron is an essential nutrient for all organisms but toxic when present in excess.
Consequently, plants carefully regulate their iron uptake, dependent on the FRO2 ferric …

Iron-induced turnover of the Arabidopsis IRON-REGULATED TRANSPORTER1 metal transporter requires lysine residues

L Kerkeb, I Mukherjee, I Chatterjee, B Lahner… - Plant …, 2008 - academic.oup.com
Iron is an essential micronutrient but is toxic if accumulated at high levels. Thus, iron uptake
and distribution in plants are controlled by precise regulatory mechanisms. IRON …

Arabidopsis IRT2 gene encodes a root‐periphery iron transporter

G Vert, JF Briat, C Curie - The Plant Journal, 2001 - Wiley Online Library
Iron uptake from the soil is a tightly controlled process in plant roots, involving specialized
transporters. One such transporter, IRT1, was identified in Arabidopsis thaliana and shown …

Altered selectivity in an Arabidopsis metal transporter

EE Rogers, DJ Eide… - Proceedings of the …, 2000 - National Acad Sciences
Plants require metals for essential functions ranging from respiration to photosynthesis.
These metals also contribute to the nutritional value of plants for both humans and livestock …

Knock-out of Arabidopsis metal transporter gene IRT1 results in iron deficiency accompanied by cell differentiation defects

R Henriques, J Jásik, M Klein, E Martinoia… - Plant molecular …, 2002 - Springer
IRT1 and IRT2 are members of the Arabidopsis ZIP metal transporter family that are
specifically induced by iron deprivation in roots and act as heterologous suppressors of …

Monoubiquitin-dependent endocytosis of the iron-regulated transporter 1 (IRT1) transporter controls iron uptake in plants

M Barberon, E Zelazny, S Robert… - Proceedings of the …, 2011 - National Acad Sciences
Plants take up iron from the soil using the IRON-REGULATED TRANSPORTER 1 (IRT1)
high-affinity iron transporter at the root surface. Sophisticated regulatory mechanisms allow …

The IRT1 protein from Arabidopsis thaliana is a metal transporter with a broad substrate range

YO Korshunova, D Eide, W Gregg Clark… - Plant molecular …, 1999 - Springer
The molecular basis for the transport of manganese across membranes in plant cells is
poorly understood. We have found that IRT1, an Arabidopsis thaliana metal ion transporter …

A novel iron-regulated metal transporter from plants identified by functional expression in yeast.

D Eide, M Broderius, J Fett… - Proceedings of the …, 1996 - National Acad Sciences
Iron is an essential nutrient for virtually all organisms. The IRT1 (iron-regulated transporter)
gene of the plant Arabidopsis thaliana, encoding a probable Fe (II) transporter, was cloned …