Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies
There has been a huge influx of data on the genetics and genomics of respiratory diseases
in the last few years. Powered by large sample sizes from collaborations worldwide, recent …
in the last few years. Powered by large sample sizes from collaborations worldwide, recent …
Pharmacogenetics and asthma: false hope or new dawn?
Pharmacogenetic approaches provide the opportunity to improve prescribing for asthmatic
patients in order to optimise efficacy and prevent side-effects. Currently, there are …
patients in order to optimise efficacy and prevent side-effects. Currently, there are …
Genetics of chronic respiratory disease
Chronic respiratory diseases, such as chronic obstructive pulmonary disease (COPD),
asthma and interstitial lung diseases are frequently occurring disorders with a polygenic …
asthma and interstitial lung diseases are frequently occurring disorders with a polygenic …
What genes tell us about the pathogenesis of asthma and chronic obstructive pulmonary disease
ST Weiss - American journal of respiratory and critical care …, 2010 - atsjournals.org
Recently a series of genome-wide association study manuscripts in asthma and chronic
obstructive pulmonary disease have been published. These papers suggest that, in part …
obstructive pulmonary disease have been published. These papers suggest that, in part …
Genetics of complex airway disease
WOC Cookson, MF Moffatt - Proceedings of the American Thoracic …, 2011 - atsjournals.org
The past 3 years have seen highly significant genetic effects identified for a wide variety of
common complex diseases, including the airway disorders of asthma and chronic …
common complex diseases, including the airway disorders of asthma and chronic …
Genetic risk factors for the development of pulmonary disease identified by genome‐wide association
Chronic respiratory diseases are a major cause of morbidity and mortality. Asthma and
chronic obstructive pulmonary disease (COPD) combined affect over 500 million people …
chronic obstructive pulmonary disease (COPD) combined affect over 500 million people …
Shared genetic aetiology of respiratory diseases: a genome-wide multitraits association analysis
Z Chen, N Gao, X Wang, X Chen… - BMJ Open …, 2024 - bmjopenrespres.bmj.com
Objective This study aims to explore the common genetic basis between respiratory
diseases and to identify shared molecular and biological mechanisms. Methods This …
diseases and to identify shared molecular and biological mechanisms. Methods This …
Recent development in genomic and proteomic research for asthma
E Halapi, H Hakonarson - Current opinion in pulmonary medicine, 2004 - journals.lww.com
The asthma genetics field has advanced considerably in recent years, with new information
being generated that has led to improved understanding of the pathobiology underlying this …
being generated that has led to improved understanding of the pathobiology underlying this …
[PDF][PDF] Respiratory medicine–genetic base for allergy and asthma
A Binia, M Kabesch - Swiss medical weekly, 2012 - smw.ch
Allergy and asthma are complex diseases influenced by many genes and molecular
mechanisms. Recently a number of genome-wide association studies (GWAS) have …
mechanisms. Recently a number of genome-wide association studies (GWAS) have …
Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets
Chronic obstructive pulmonary disease (COPD) is characterized by reduced lung function
and is the third leading cause of death globally. Through genome-wide association …
and is the third leading cause of death globally. Through genome-wide association …