Production of adventitious roots and secondary metabolites by Hypericum perforatum L. in a bioreactor

XH Cui, D Chakrabarty, EJ Lee, KY Paek - Bioresource technology, 2010 - Elsevier
We investigated the effects of different concentrations of auxin and auxin/cytokinin
combinations, inoculum sizes and Murashige and Skoog (MS) medium dilutions on biomass …

Production of adventitious root biomass and secondary metabolites of Hypericum perforatum L. in a balloon type airlift reactor

XH Cui, HN Murthy, YX Jin, YH Yim, JY Kim… - Bioresource …, 2011 - Elsevier
The effects of inoculum density, aeration volume and culture period on accumulation of
biomass and secondary metabolites in adventitious roots of Hypericum perforatum in …

Pilot-Scale Culture of Hypericum Perforatum L. Adventitious Roots in Airlift Bioreactors for the Production of Bioactive Compounds

XH Cui, HN Murthy, KY Paek - Applied biochemistry and biotechnology, 2014 - Springer
Abstract Hypericum perforatum L.(St. John's Wort) is an important medicinal plant which is
widely used in the treatment for depression and irritable bowel syndrome. It is also used as a …

Adventitious root suspension cultures of Hypericum perforatum: effect of nitrogen source on production of biomass and secondary metabolites

XH Cui, HN Murthy, CH Wu, KY Paek - In Vitro Cellular & Developmental …, 2010 - Springer
The present study investigated the effect of nitrogen source (NH 4+; NO 3−) at different
concentrations on the accumulation of biomass and secondary metabolites in adventitious …

Several factors affecting hypericin production of Hypericum perforatum during adventitious root culture in airlift bioreactors

SQ Wu, XK Yu, ML Lian, SY Park, XC Piao - Acta physiologiae plantarum, 2014 - Springer
Hypericum perforatum L. is a traditional medicinal plant for the treatment of depression and
wound healing, and hypericin is one of the main effective active substances. To optimize the …

Identification and quantification of hypericin and pseudohypericin in different Hypericum perforatum L. in vitro cultures

S Gadzovska, S Maury, S Ounnar, M Righezza… - Plant Physiology and …, 2005 - Elsevier
Investigations have been made to develop an efficient protocol for micropropagation
allowing to improve hypericin and pseudohypericin productions in Hypericum perforatum L …

Production of hypericin, pseudohypericin and flavonoids in cell cultures of various Hypericum species and their chemotypes

T Kartnig, I Göbel, B Heydel - Planta Medica, 1996 - thieme-connect.com
Suspension cultures were established from the shoots of sterile germinated seeds of various
provenances of seven Hypericum (H.) species in a half strength modified Murashige and …

Multiple shoot formation in Hypericum perforatum L. and hypericin production

ER Santarém, LV Astarita - Brazilian journal of plant physiology, 2003 - SciELO Brasil
Hypericum perforatum is a traditional medicinal plant with wound healing and
antidepressive properties. Among the secondary compounds of interest is hypericin, a …

Secondary metabolism in micropropagated Hypericum perforatum L. grown in non-aerated liquid medium

LEB Savio, LV Astarita, ER Santarém - Plant cell, tissue and organ culture …, 2012 - Springer
Hypericum perforatum L. is a medicinal plant that has been extensively studied because of
its bioactive properties. The objective of this study was to establish a system that could lower …

In vitro production and chemical characterization of St. John's wort (Hypericum perforatum L. cv 'New Stem')

SMA Zobayed, SJ Murch, HPV Rupasinghe… - Plant Science, 2004 - Elsevier
Hypericum perforatum L.(St. John's wort) is a traditional medicinal plant that has been used
for the treatment of neurological disorders and depression. To investigate a large-scale in …