Curcumin as a therapeutic agent for blocking NF-κB activation in ulcerative colitis

Y Wang, Q Tang, P Duan, L Yang - Immunopharmacology and …, 2018 - Taylor & Francis
Ulcerative colitis (UC) is a chronic, relapsing, remitting, and inflammatory disorder that
afflicts millions of people around the world. It carries a substantial economic burden …

Curcumin has bright prospects for the treatment of inflammatory bowel disease

H Hanai, K Sugimoto - Current pharmaceutical design, 2009 - ingentaconnect.com
Inflammatory bowel disease (IBD) is a chronic relapsing-remitting condition that afflicts
millions of people throughout the world and impairs their daily functions and quality of life …

[HTML][HTML] Preventive and therapeutic effects of NF-kappaB inhibitor curcumin in rats colitis induced by trinitrobenzene sulfonic acid

YT Jian, GF Mai, JD Wang, YL Zhang… - World journal of …, 2005 - ncbi.nlm.nih.gov
AIM: To ascertain the molecule mechanism of nuclear factor-κB (NF-κB) inhibitor curcumin
preventive and therapeutic effects in rats' colitis induced by trinitrobenzene sulfonic acid …

Curcumin, an active component of turmeric in the prevention and treatment of ulcerative colitis: preclinical and clinical observations

MS Baliga, N Joseph, MV Venkataranganna… - Food & function, 2012 - pubs.rsc.org
Inflammatory bowel disease (IBD) comprising of ulcerative colitis (UC) and Crohn's disease
(CD) is a major ailment affecting the small and large bowel. In clinics, IBD is treated using 5 …

Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis

L Camacho-Barquero, I Villegas… - International …, 2007 - Elsevier
Ulcerative colitis (UC) is a nonspecific inflammatory disorder characterized by oxidative and
nitrosative stress, leucocyte infiltration and up-regulation of pro-inflammatory cytokines …

The effect of curcumin supplementation on clinical outcomes and inflammatory markers in patients with ulcerative colitis

N Sadeghi, A Mansoori, A Shayesteh… - Phytotherapy …, 2020 - Wiley Online Library
Background and aims Curcumin has anti‐inflammatory properties. The aim of this study was
to evaluate the effect of curcumin on improvement of the disease activity in ulcerative colitis …

Curcumin prevents and ameliorates trinitrobenzene sulfonic acid–induced colitis in mice

K Sugimoto, H Hanai, K Tozawa, T Aoshi, M Uchijima… - Gastroenterology, 2002 - Elsevier
Background & Aims: Curcumin is known to have a variety of pharmacologic effects, including
antitumor, anti-inflammatory, and anti-infectious activities. The pleiotropic effects of curcumin …

Review of the effects and mechanism of curcumin in the treatment of inflammatory bowel disease

Y Lin, H Liu, L Bu, C Chen, X Ye - Frontiers in Pharmacology, 2022 - frontiersin.org
Curcumin is extracted from the rhizomes of Curcuma longa L. It is now widely used in food
processing, cosmetics, dyes, etc. Current researching indicates that curcumin has high …

Curcumin and its modified formulations on inflammatory bowel disease (IBD): The story so far and future outlook

A Karthikeyan, KN Young, M Moniruzzaman… - Pharmaceutics, 2021 - mdpi.com
Inflammatory bowel disease (IBD) is a chronic relapsing and remitting inflammatory disorder
of the small intestine and colon. IBD includes ulcerative colitis (UC) and Crohn's disease …

Limited effects of dietary curcumin on Th-1 driven colitis in IL-10 deficient mice suggest an IL-10-dependent mechanism of protection

CB Larmonier, JK Uno, KM Lee… - American journal …, 2008 - journals.physiology.org
Curcumin (diferulolylmethane) demonstrates profound anti-inflammatory effects in intestinal
epithelial cells (IEC) and in immune cells in vitro and exhibits a protective role in rodent …