Mitochondrial dysfunction contributes to the pathogenesis of Alzheimer's disease
FA Cabezas-Opazo, K Vergara-Pulgar… - Oxidative medicine …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is a neurodegenerative disease that affects millions of people
worldwide. Currently, there is no effective treatment for AD, which indicates the necessity to …
worldwide. Currently, there is no effective treatment for AD, which indicates the necessity to …
[HTML][HTML] Mitochondrial dysfunction and oxidative stress in Alzheimer's disease
A Misrani, S Tabassum, L Yang - Frontiers in aging neuroscience, 2021 - frontiersin.org
Mitochondria play a pivotal role in bioenergetics and respiratory functions, which are
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …
essential for the numerous biochemical processes underpinning cell viability. Mitochondrial …
Mitochondria dysfunction in the pathogenesis of Alzheimer's disease: Recent advances
Alzheimer's disease (AD) is one of the most prevalent neurodegenerative diseases,
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
characterized by impaired cognitive function due to progressive loss of neurons in the brain …
Alzheimer's pathogenesis and its link to the mitochondrion
C Simoncini, D Orsucci… - Oxidative medicine …, 2015 - Wiley Online Library
Alzheimer's disease (AD) is the most common form of dementia in the elderly. This
neurodegenerative disorder is clinically characterized by impairment of cognitive functions …
neurodegenerative disorder is clinically characterized by impairment of cognitive functions …
Mitochondrial cascade hypothesis of Alzheimer's disease: myth or reality?
Mitochondria are recognized to play a pivotal role in neuronal cell survival or death because
they are regulators of both energy metabolism and apoptotic pathways. Morphologic …
they are regulators of both energy metabolism and apoptotic pathways. Morphologic …
[HTML][HTML] Relationships between mitochondrial dysfunction and neurotransmission failure in Alzheimer's disease
Besides extracellular deposition of amyloid beta and formation of phosphorylated tau in the
brains of patients with Alzheimer's disease (AD), the pathogenesis of AD is also thought to …
brains of patients with Alzheimer's disease (AD), the pathogenesis of AD is also thought to …
Mitochondrial dysfunction: a potential therapeutic target to treat Alzheimer's disease
Mitochondrial dysfunction plays a very vital role in the pathogenesis of Alzheimer's disease
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …
(AD). Several shreds of evidence have indicated that the mitochondrial function is severely …
Mitochondrial dysfunction: common final pathway in brain aging and Alzheimer's disease—therapeutic aspects
As a fully differentiated organ, our brain is very sensitive to cumulative oxidative damage of
proteins, lipids, and DNA occurring during normal aging because of its high energy …
proteins, lipids, and DNA occurring during normal aging because of its high energy …
Mechanisms of mitochondrial dysfunction in Alzheimer's disease
C Cadonic, MG Sabbir, BC Albensi - Molecular neurobiology, 2016 - Springer
Mitochondria are the primary source for energy generation in the cell, which manifests itself
in the form of the adenosine triphosphate (ATP). Nicotinamide dinucleotide (NADH) …
in the form of the adenosine triphosphate (ATP). Nicotinamide dinucleotide (NADH) …
The role of mitochondrial dysfunction in Alzheimer's disease: a potential pathway to treatment
AB Reiss, S Ahmed, C Dayaramani, AD Glass… - Experimental …, 2022 - Elsevier
Background Alzheimer's disease (AD) is the most prevalent form of dementia worldwide and
is characterized by progressive memory loss and cognitive impairment. Our understanding …
is characterized by progressive memory loss and cognitive impairment. Our understanding …