Pyroptosis is identified as a pro-inflammatory programmed cell death, mediated by
gasdermins (GSDMs) family of proteins accompanied by pro-inflammatory signals release …

Pyroptosis is a recently identified mechanism of programmed cell death related to Caspase-
1 that triggers a series of inflammatory reactions by releasing several proinflammatory …

Pyroptosis is a recently identified type of lytic programmed cell death, in which pores form in
the plasma membrane, and cells swell, rupture, and then release their contents, including …

Diabetic nephropathy (DN), a sterile inflammatory disease, is a serious complication of
diabetes mellitus. However, recent evidence indicates that pyroptosis, a new term for pro …

Diabetic nephropathy (DN) is one of the serious chronic microvascular complications of
diabetes, and leads to the increased morbidity and mortality in diabetic patients. Gasdermin …

Diabetic nephropathy (DN) is the main cause of end-stage renal disease (ESRD), which is
characterized by a series of abnormal changes such as glomerulosclerosis, podocyte loss …

Pyroptosis is one special type of lytic programmed cell death, featured in cell swelling,
rupture, secretion of cell contents and remarkable proinflammation effect. In the process of …

We recently found that Sodium butyrate (NaB) possesses anti-inflammatory effects in
diabetic nephropathy (DN) mouse model and in high-glucose induced mouse glomerular …

Significance: Kidney diseases remain a worldwide public health problem resulting in
millions of deaths each year; they are characterized by progressive destruction of renal …

Pyroptosis is a form of cell death mediated by gasdermin D (GSDMD); it is characterised by
NLRP3 inflammasome activation, caspase activation, cell membrane pore formation, and …